Oncological Frontiers in the Treatment of Malignant Pleural Mesothelioma

Emanuele Vita, Alessio Stefani, Mariantonietta Di Salvatore, Marco Chiappetta, Filippo Lococo, Stefano Margaritora, Giampaolo Tortora, Emilio Bria

Research output: Contribution to journalArticle


Malignant pleural mesothelioma (MPM) is a rare malignancy characterized by very poor prognosis and lack of treatment options. Immunotherapy has rapidly emerged as an effective tool for MPM, particularly for tumors of non-epithelioid histology. At the same time, comprehensive genomic sequencing may open the way to new-generation targeted-drugs able to hit specific MPM molecular vulnerabilities. These innovations will possibly enrich, but also dramatically complicate, the elucidation of treatment algorithms. Multidisciplinary integration is urgently needed.
Original languageEnglish
Pages (from-to)N/A-N/A
JournalJournal of Clinical Medicine
Publication statusPublished - 2021


  • immunotherapy
  • malignant pleural mesothelioma
  • target therapy


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