Ocular palsies in the absence of other neurological or ocular symptoms: analysis of 105 cases

Amelia Evoli, Luca Padua, Enzo Ricci, Anna Paola Batocchi, Mauro Lo Monaco, Anna Dickmann Rossi, L Majolini, Pietro Attilio Tonali

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48 Citations (Scopus)

Abstract

We studied prospectively 105 unselected patients complaining of ptosis and/or diplopia due to extrinsic ophthalmic muscle palsies without other neurological signs. All patients underwent the same diagnostic protocol. The presenting symptoms were: ptosis, 35 patients (33%); diplopia, 27 patients (26%); ptosis and diplopia, 43 patients (41%). The oculomotor nerve was most frequently involved, followed by the abducens nerve. The final diagnoses were: ocular myasthenia, intracranial and/or orbital pathology, thyroid ophthalmopathy, diabetic ophthalmoplegia, mitochondrial myopathy, oculopharyngeal muscular dystrophy. In 26 patients (25%) the cause remained undetermined. Our study confirms the difficulty of establishing an aetiological diagnosis in patients with isolated ocular palsies.
Original languageEnglish
Pages (from-to)639-645
Number of pages7
JournalJournal of Neurology
Volume244
Publication statusPublished - 1997

Keywords

  • Abducens Nerve
  • Diplopia
  • Ocular Motility Disorders
  • Oculomotor Nerve Diseases
  • Prospective Studies

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