Novel TOP3A Variant Associated With Mitochondrial Disease: Expanding the Clinical Spectrum of Topoisomerase III Alpha-Related Diseases

Medicine and Dentistry

• Diseases 100%
• Gene 80%
• Phenotype 40%
• Mitochondrial DNA 40%
• Bloom Syndrome 40%
• Analysis 40%
• Exercise Intolerance 20%
• Muscle Biopsy 20%
• Creatine Kinase 20%
• Mitochondrial Myopathy 20%
• Topoisomerase 20%
• Chronic Progressive External Ophthalmoplegia 20%
• Next Generation Sequencing 20%
• Holliday Junction 20%
• Mitochondrial DNA Replication 20%
• Assessment 20%
• Hospital 20%
• Patient 20%
• Adult 20%
• Woman 20%
• Syndrome 20%