New-Onset Diabetes in Covid-19

Francesco Rubino; Stephanie A. Amiel; Paul Zimmet; George Alberti; Stefan Bornstein; Robert H. Eckel; Geltrude Mingrone; Bernhard Boehm; Mark E. Cooper; Zhonglin Chai; Stefano Del Prato; Linong Ji; David Hopkins; William H. Herman; Kamlesh Khunti; Jean-Claude Mbanya

doi:10.1056/NEJMc2018688

New-Onset Diabetes in Covid-19

Francesco Rubino, Stephanie A. Amiel, Paul Zimmet, George Alberti, Stefan Bornstein, Robert H. Eckel, Geltrude Mingrone, Bernhard Boehm, Mark E. Cooper, Zhonglin Chai, Stefano Del Prato, Linong Ji, David Hopkins, William H. Herman, Kamlesh Khunti, Jean-Claude Mbanya

Research output: Contribution to journal › Article

160 Citations (SciVal)

Abstract

There is a bidirectional relationship between Covid-19 and diabetes. On the one hand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, new-onset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3 These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.

Original language	English
Pages (from-to)	789-791
Number of pages	3
Journal	THE NEW ENGLAND JOURNAL OF MEDICINE
Volume	383
DOIs	https://doi.org/10.1056/NEJMc2018688
Publication status	Published - 2020

Keywords

Betacoronavirus
COVID-19
Coronavirus Infections
Diabetes Complications
Diabetes Mellitus
Global Health
Glucose
Humans
Pandemics
Pneumonia, Viral
Registries
SARS-CoV-2

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1056/NEJMc2018688

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title = "New-Onset Diabetes in Covid-19",

abstract = "There is a bidirectional relationship between Covid-19 and diabetes. On the one hand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, new-onset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3 These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.",

keywords = "Betacoronavirus, COVID-19, Coronavirus Infections, Diabetes Complications, Diabetes Mellitus, Global Health, Glucose, Humans, Pandemics, Pneumonia, Viral, Registries, SARS-CoV-2, Betacoronavirus, COVID-19, Coronavirus Infections, Diabetes Complications, Diabetes Mellitus, Global Health, Glucose, Humans, Pandemics, Pneumonia, Viral, Registries, SARS-CoV-2",

author = "Francesco Rubino and Amiel, {Stephanie A.} and Paul Zimmet and George Alberti and Stefan Bornstein and Eckel, {Robert H.} and Geltrude Mingrone and Bernhard Boehm and Cooper, {Mark E.} and Zhonglin Chai and Prato, {Stefano Del} and Linong Ji and David Hopkins and Herman, {William H.} and Kamlesh Khunti and Jean-Claude Mbanya",

year = "2020",

doi = "10.1056/NEJMc2018688",

language = "English",

volume = "383",

pages = "789--791",

journal = "THE NEW ENGLAND JOURNAL OF MEDICINE",

issn = "0028-4793",

publisher = "Boston: Massachusetts Medical Society",

}

TY - JOUR

T1 - New-Onset Diabetes in Covid-19

AU - Rubino, Francesco

AU - Amiel, Stephanie A.

AU - Zimmet, Paul

AU - Alberti, George

AU - Bornstein, Stefan

AU - Eckel, Robert H.

AU - Mingrone, Geltrude

AU - Boehm, Bernhard

AU - Cooper, Mark E.

AU - Chai, Zhonglin

AU - Prato, Stefano Del

AU - Ji, Linong

AU - Hopkins, David

AU - Herman, William H.

AU - Khunti, Kamlesh

AU - Mbanya, Jean-Claude

PY - 2020

Y1 - 2020

N2 - There is a bidirectional relationship between Covid-19 and diabetes. On the one hand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, new-onset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3 These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.

AB - There is a bidirectional relationship between Covid-19 and diabetes. On the one hand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, new-onset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3 These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.

KW - Betacoronavirus

KW - COVID-19

KW - Coronavirus Infections

KW - Diabetes Complications

KW - Diabetes Mellitus

KW - Global Health

KW - Glucose

KW - Humans

KW - Pandemics

KW - Pneumonia, Viral

KW - Registries

KW - SARS-CoV-2

KW - Betacoronavirus

KW - COVID-19

KW - Coronavirus Infections

KW - Diabetes Complications

KW - Diabetes Mellitus

KW - Global Health

KW - Glucose

KW - Humans

KW - Pandemics

KW - Pneumonia, Viral

KW - Registries

KW - SARS-CoV-2

UR - http://hdl.handle.net/10807/167602

U2 - 10.1056/NEJMc2018688

DO - 10.1056/NEJMc2018688

M3 - Article

SN - 0028-4793

VL - 383

SP - 789

EP - 791

JO - THE NEW ENGLAND JOURNAL OF MEDICINE

JF - THE NEW ENGLAND JOURNAL OF MEDICINE

ER -

New-Onset Diabetes in Covid-19

Abstract

Keywords

UN SDGs

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