Necrotizing granulomata of the aortic valve in Wegener's disease

P Bruno, C Le Hello, Massimo Massetti, G Babatasi, E Saloux, F Galateau, A. Khayat

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17 Citations (Scopus)


Wegener's disease is an inflammatory disease of unknown etiology, characterized by a granulomatous-necrotizing general vasculitis. Cardiac involvement in the form of aortic pathology is not frequent. We report a case of Wegener's granulomatosis which required prosthetic aortic valve replacement for aortic valve insufficiency. Microscopic examination of the valve demonstrated histopathology typical of Wegener's disease.
Original languageEnglish
Pages (from-to)633-635
Number of pages3
JournalJournal of Heart Valve Disease
Publication statusPublished - 2000


  • Aortic Valve
  • Aortic Valve Insufficiency
  • Female
  • Granulomatosis with Polyangiitis
  • Heart Valve Prosthesis Implantation
  • Humans
  • Middle Aged
  • Necrosis


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