36 Citations (Scopus)

Abstract

The pathogenesis of the hydrocephalus associated with myelomeningocele (MMC) has been the subject of an extensive number of studies. The contemporary reduction of the incidence of the Chiari II malformation and of the associated active hydrocephalus after closure of the spinal defect in utero is in line with previous studies suggesting a prominent role of the posterior cranial fossa abnormalities, where even the increased venous pressure might be at least mostly a consequence of the constriction of the posterior cranial fossa structures. Pure absorptive abnormalities however coexist, the main ones documented to be abnormal cisternal spaces and peculiar cerebrospinal fluid chemical features.
Original languageEnglish
Pages (from-to)1569-1579
Number of pages11
JournalCHILD'S NERVOUS SYSTEM
Volume29
DOIs
Publication statusPublished - 2013

Keywords

  • hydrocephalus

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