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multiple viral genome search in endolabyrinthic fluids of profoundly deaf patients: possible cytomegalovirus intracochlear reactivation

  • Walter Di Nardo
  • , Paola Cattani Franchi
  • , Teresa Lopizzo
  • , Italo Cantore
  • , Maria Raffaella Marchese
  • , Simona Marchetti
  • , Alessandro Scorpecci
  • , Sara Giannantonio
  • , Claudio Parrilla
  • , Francesca Cianfrone
  • , Giovanni Fadda
  • , Gaetano Paludetti

Research output: Contribution to journal › Article › peer-review

Abstract

In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.
Original languageEnglish
Pages (from-to)290-295
Number of pages6
JournalAudioogyl & neurootology
Volume14
Publication statusPublished - 2009

Keywords

  • CYTOMEGALOVIRUS
  • ENDOLABYRINTHIC FLUID

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