Multiple vertebral fractures precipitate a platypnea-orthodeoxia syndrome in a patient with atrial septal defect and aortic root dilatation: when the upright position becomes intolerable

Leonarda Galiuto, Filippo Crea, Gabriella Locorotondo, Lazzaro Paraggio, Antonio Giuseppe Rebuzzi, Elisa Fedele, M. Ludovica Danza, Elena De Vito, Ambra Masi

Research output: Contribution to journalArticlepeer-review

Abstract

Platypnea-orthodeoxia syndrome is a rare disease characterized by dyspnea and oxygen desaturation induced by the upright position and relieved by recumbency. We report a case of 65- years old woman with a recent history of traumatic hip and multiple vertebral fractures referred to our Institute due to onset of severe acute dyspnea. Trans-thoracic and trans-oesophageal echocardiography, conducted by intravenous administration of agitated saline contrast solution, revealed the presence of Atrial Septal Defect (ASD) associated with an important bidirectional shunting that was right-to-left directed when the patient was in sitting position. Surgical closure of ASD resulted in resolution of the syndrome
Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalJournal of Cardiology
DOIs
Publication statusPublished - 2012

Keywords

  • PLATYPNEA-ORTHODEOXIA SYNDROME

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