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Modeling sarcopenia: a geriatric disease of skeletal muscle tissue

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We propose a continuum model of skeletal muscle tissue with a reduced performance due to ageing.\r\n The passive behavior of the material is described by a hyperelastic, polyconvex, transversely isotropic\r\n strain energy function, and the activation of the muscle is modeled by the so called active strain\r\n approach. The loss of ability of activating of an elder muscle is then obtained by lowering of some\r\n percentage the active part of the stress, while the loss of mass is modeled through a multiplicative\r\n decomposition of the deformation gradient.
Original languageEnglish
Title of host publication5th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2017
PublisherZeta Computational Resources Ltd.
Pages400-402
Number of pages3
Publication statusPublished - 2017

Keywords

  • active strain
  • damage
  • hyperelasticity
  • sarcopenia

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