METABOLIC SYNDROME IN TRANSPLANT PATIENTS: AN UPDATING POINT OF VIEW

Andrea Giaccari, Teresa Mezza, Alfredo Pontecorvi, Gianpio Sorice, Giovanna Muscogiuri, Annamaria Prioletta, A. Prioletta

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Metabolic Syndrome is a cluster of risk factors that predispose individuals to major cardiovascular diseases and its complications, determining liver and kidney impairment. In the last decade, the indications to transplantation are increasing, with a linear incidence of the complications of the procedure. Metabolic syndrome represents one of the most common, being in turn the consequence of the underlying disease that required the transplantation, or the result of the medical treatment, as well as one of the most important factor influencing the morbidity and mortality of the transplanted patients. Due to the growing incidence of the metabolic syndrome in these patients, it is crucial to focus and clarify the leading causes determining the onset of the metabolic disarrangement, its outcome and the hypothetical mechanism through which the clinicians could reduce the impact of the disease. In fact, prevention, early recognition and treatment of the factor that could predict the onset or progression of the metabolic syndrome after the transplantation may impact long term survival of patients again, the scope of the same transplant. This review will update the different mechanisms of the pathogenesis of metabolic syndrome in this population, the clinical effects of the presence of the metabolic syndrome, observing the risk factors to be treated before and after the transplantation and suggesting the management of the follow-up.
Original languageEnglish
Pages (from-to)N/A-N/A
JournalMinerva Medica
Publication statusPublished - 2012

Keywords

  • METABOLIC SYNDROME
  • TRANSPLANTATION

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