Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

Angela Santoro; Giuseppe Angelico; Vincenzo Fiorentino; Qianqian Zhang; Saveria Spadola; Angela Carlino; Alejandro Martin Sanchez; Gianluca Franceschini; Gian Franco Zannoni; Antonino Mulè

doi:10.3390/diagnostics11040709

Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

Angela Santoro
, Giuseppe Angelico
, Vincenzo Fiorentino
, Qianqian Zhang
, Saveria Spadola
, Angela Carlino
, Alejandro Martin Sanchez
, Gianluca Franceschini
, Gian Franco Zannoni^*
, Antonino Mulè

^*Corresponding author

Research output: Contribution to journal › Article

Abstract

Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional\r\nclinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral\r\ngrowth factors are considered essential.

Original language	English
Pages (from-to)	709-709
Number of pages	9
Journal	Diagnostics
Volume	11
Issue number	11 (4)
DOIs	https://doi.org/10.3390/diagnostics11040709
Publication status	Published - 2021

All Science Journal Classification (ASJC) codes

Internal Medicine
Clinical Biochemistry

Keywords

breast carcinoma
breast melanosis
melanocyte colonization
melanoma
pigmentation

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10.3390/diagnostics11040709

Cite this

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title = "Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature",

abstract = "Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional\textbackslash{}r\textbackslash{}nclinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral\textbackslash{}r\textbackslash{}ngrowth factors are considered essential.",

keywords = "breast carcinoma, breast melanosis, melanocyte colonization, melanoma, pigmentation, breast carcinoma, breast melanosis, melanocyte colonization, melanoma, pigmentation",

author = "Angela Santoro and Giuseppe Angelico and Vincenzo Fiorentino and Qianqian Zhang and Saveria Spadola and Angela Carlino and Sanchez, \{Alejandro Martin\} and Gianluca Franceschini and Zannoni, \{Gian Franco\} and Antonino Mul{\`e}",

year = "2021",

doi = "10.3390/diagnostics11040709",

language = "English",

volume = "11",

pages = "709--709",

journal = "Diagnostics",

issn = "2075-4418",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "11 (4)",

}

TY - JOUR

T1 - Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

AU - Santoro, Angela

AU - Angelico, Giuseppe

AU - Fiorentino, Vincenzo

AU - Zhang, Qianqian

AU - Spadola, Saveria

AU - Carlino, Angela

AU - Sanchez, Alejandro Martin

AU - Franceschini, Gianluca

AU - Zannoni, Gian Franco

AU - Mulè, Antonino

PY - 2021

Y1 - 2021

N2 - Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional\r\nclinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral\r\ngrowth factors are considered essential.

AB - Colonization of breast carcinoma by non-neoplastic melanocytes of epidermal origin was first described by Azzopardi and Eusebi in 1977. We herein report two cases on the exceptional\r\nclinical and pathological features of this phenomenon in a 66-year-old and a 51-year-old patients. The pathogenesis is not fully understood, but a disrupted basement membrane and the role of tumoral\r\ngrowth factors are considered essential.

KW - breast carcinoma

KW - breast melanosis

KW - melanocyte colonization

KW - melanoma

KW - pigmentation

KW - breast carcinoma

KW - breast melanosis

KW - melanocyte colonization

KW - melanoma

KW - pigmentation

UR - https://publicatt.unicatt.it/handle/10807/178081

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U2 - 10.3390/diagnostics11040709

DO - 10.3390/diagnostics11040709

M3 - Article

SN - 2075-4418

VL - 11

SP - 709

EP - 709

JO - Diagnostics

JF - Diagnostics

IS - 11 (4)

ER -

Melanocyte Colonization and Pigmentation of Breast Carcinoma: Description of Two Pathological Cases and Review of Literature

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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