Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia

Federica Sora', Patrizia Chiusolo, Luca Laurenti, Francesco Autore, Sabrina Giammarco, Simona Sica

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4 Citations (Scopus)


Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with thrombolysis for PE and heparin. APL has been processed with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) obtaining complete remission.
Original languageEnglish
Pages (from-to)e2016027-e2016027
JournalMediterranean Journal of Hematology and Infectious Diseases
Publication statusPublished - 2016


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