Markedly Increased 18F-FDG Uptake in a Nonfunctioning Adrenal Adenoma Mimicking Malignancy

Giorgio Treglia; Luigi Oragano; Guido Fadda; Anna Maria De Gaetano; Marco Raffaelli; Vittoria Rufini

doi:10.1097/RLU.0b013e318279f389

Markedly Increased 18F-FDG Uptake in a Nonfunctioning Adrenal Adenoma Mimicking Malignancy

Giorgio Treglia, Luigi Oragano, Guido Fadda, Anna Maria De Gaetano, Marco Raffaelli, Vittoria Rufini

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

A 63-year-old woman underwent F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake in the right adrenal gland; this finding was suspicious for an adrenal malignancy or a functioning adenoma. Nevertheless, histology and laboratory data demonstrated the presence of a nonfunctioning adenoma. This case highlights that nonfunctioning adrenal adenomas should be considered as possible false-positive F-FDG PET/CT findings for malignancy in the evaluation of adrenal incidentalomas, even when marked F-FDG uptake is revealed.

Original language	English
Pages (from-to)	e333-e335
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	38
DOIs	https://doi.org/10.1097/RLU.0b013e318279f389
Publication status	Published - 2013

Keywords

adrenal adenoma
adrenal gland

Access to Document

10.1097/RLU.0b013e318279f389

Cite this

@article{ffe2cb009db0467b93a9e76bd9ee7424,

title = "Markedly Increased 18F-FDG Uptake in a Nonfunctioning Adrenal Adenoma Mimicking Malignancy",

abstract = "A 63-year-old woman underwent F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake in the right adrenal gland; this finding was suspicious for an adrenal malignancy or a functioning adenoma. Nevertheless, histology and laboratory data demonstrated the presence of a nonfunctioning adenoma. This case highlights that nonfunctioning adrenal adenomas should be considered as possible false-positive F-FDG PET/CT findings for malignancy in the evaluation of adrenal incidentalomas, even when marked F-FDG uptake is revealed.",

keywords = "adrenal adenoma, adrenal gland, adrenal adenoma, adrenal gland",

author = "Giorgio Treglia and Luigi Oragano and Guido Fadda and {De Gaetano}, {Anna Maria} and Marco Raffaelli and Vittoria Rufini",

year = "2013",

doi = "10.1097/RLU.0b013e318279f389",

language = "English",

volume = "38",

pages = "e333--e335",

journal = "Clinical Nuclear Medicine",

issn = "0363-9762",

publisher = "Lippincott Williams and Wilkins Ltd.",

}

TY - JOUR

T1 - Markedly Increased 18F-FDG Uptake in a Nonfunctioning Adrenal Adenoma Mimicking Malignancy

AU - Treglia, Giorgio

AU - Oragano, Luigi

AU - Fadda, Guido

AU - De Gaetano, Anna Maria

AU - Raffaelli, Marco

AU - Rufini, Vittoria

PY - 2013

Y1 - 2013

N2 - A 63-year-old woman underwent F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake in the right adrenal gland; this finding was suspicious for an adrenal malignancy or a functioning adenoma. Nevertheless, histology and laboratory data demonstrated the presence of a nonfunctioning adenoma. This case highlights that nonfunctioning adrenal adenomas should be considered as possible false-positive F-FDG PET/CT findings for malignancy in the evaluation of adrenal incidentalomas, even when marked F-FDG uptake is revealed.

AB - A 63-year-old woman underwent F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake in the right adrenal gland; this finding was suspicious for an adrenal malignancy or a functioning adenoma. Nevertheless, histology and laboratory data demonstrated the presence of a nonfunctioning adenoma. This case highlights that nonfunctioning adrenal adenomas should be considered as possible false-positive F-FDG PET/CT findings for malignancy in the evaluation of adrenal incidentalomas, even when marked F-FDG uptake is revealed.

KW - adrenal adenoma

KW - adrenal gland

KW - adrenal adenoma

KW - adrenal gland

UR - http://hdl.handle.net/10807/43361

U2 - 10.1097/RLU.0b013e318279f389

DO - 10.1097/RLU.0b013e318279f389

M3 - Article

SN - 0363-9762

VL - 38

SP - e333-e335

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

ER -

Markedly Increased 18F-FDG Uptake in a Nonfunctioning Adrenal Adenoma Mimicking Malignancy

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this