TY - JOUR
T1 - Management of Small Bowel Obstruction (SBO) in older adults (=80 years): a propensity score- matched analysis on predictive factors for a (un) successful non-operative management (NOM)
AU - Rosa, Fausto
AU - Covino, Marcello
AU - Fransvea, Pietro
AU - Quero, Giuseppe
AU - Pacini, Giovanni
AU - Fiorillo, Claudio
AU - Simeoni, B
AU - La Greca, Antonio
AU - Sganga, Gabriele
AU - Franceschi, Francesco
AU - Gasbarrini, Antonio
AU - Alfieri, Sergio
PY - 2022
Y1 - 2022
N2 - OBJECTIVE: Small Bowel Obstruction (SBO) is a common emergency in older patients. The most appropriate treatment strategy is still matter of debate. The aim of this study was to compare a non-operative management (NOM) vs. a surgical procedure for patients >= 80 years with SBO. PATIENTS AND METHODS: All patients >= 80 years admitted to our Emergency Department (ED) for SBO between January 1st, 2015, and December 31st, 2020 were included in this study. In order to correct for baseline covariates and factors associated to clinical management, we used a 1:1 propensity score matching (PSM) analysis. The primary outcome was to compare the over-all in-hospital mortality. Secondary outcomes included occurrence of major complications and in-hospital length of stay (LOS). RESULTS: A total of 561 patients were en-rolled. After propensity score matching (PSM) analysis, 302 patients (151 each group) were included in the analysis. Mortality did not differ between the two groups. After PSM mechanical ventilation, sepsis, cumulative major complications, and LOS were significantly higher in the operative treatment group [15.9% vs. 1.5%, 9.4% vs. 4.1%, 27.6% vs. 19.2%, and 9.4 (6.4-14.3) days vs. 8.1 (4.5-13.3) days, respectively; p < 0.001, p=0.013, p=0.025, and p=0.003, respectively]. CONCLUSIONS: In patients >= 80 years with SBO, a NOM could yield similar results, in terms of overall mortality, compared to a surgical management. Thus, particularly in patients with multiple comorbidities or functional impairments, a conservative approach should always be considered.
AB - OBJECTIVE: Small Bowel Obstruction (SBO) is a common emergency in older patients. The most appropriate treatment strategy is still matter of debate. The aim of this study was to compare a non-operative management (NOM) vs. a surgical procedure for patients >= 80 years with SBO. PATIENTS AND METHODS: All patients >= 80 years admitted to our Emergency Department (ED) for SBO between January 1st, 2015, and December 31st, 2020 were included in this study. In order to correct for baseline covariates and factors associated to clinical management, we used a 1:1 propensity score matching (PSM) analysis. The primary outcome was to compare the over-all in-hospital mortality. Secondary outcomes included occurrence of major complications and in-hospital length of stay (LOS). RESULTS: A total of 561 patients were en-rolled. After propensity score matching (PSM) analysis, 302 patients (151 each group) were included in the analysis. Mortality did not differ between the two groups. After PSM mechanical ventilation, sepsis, cumulative major complications, and LOS were significantly higher in the operative treatment group [15.9% vs. 1.5%, 9.4% vs. 4.1%, 27.6% vs. 19.2%, and 9.4 (6.4-14.3) days vs. 8.1 (4.5-13.3) days, respectively; p < 0.001, p=0.013, p=0.025, and p=0.003, respectively]. CONCLUSIONS: In patients >= 80 years with SBO, a NOM could yield similar results, in terms of overall mortality, compared to a surgical management. Thus, particularly in patients with multiple comorbidities or functional impairments, a conservative approach should always be considered.
KW - Small Bowel Obstruction
KW - Elderly
KW - Mortality
KW - Non-operative management (NOM)
KW - Morbidity
KW - Surgery
KW - Small Bowel Obstruction
KW - Elderly
KW - Mortality
KW - Non-operative management (NOM)
KW - Morbidity
KW - Surgery
UR - http://hdl.handle.net/10807/224407
M3 - Article
SN - 1128-3602
VL - 26
SP - 7219
EP - 7228
JO - European Review for Medical and Pharmacological Sciences
JF - European Review for Medical and Pharmacological Sciences
ER -