Low prevalence of human papillomavirus infection in the healthy oral mucosa of a Northern Italian population

Alessandro Sgambato, M. Migaldi, M. Pecorari, G. Forbicini, N. Nanni, A. Grottola, T. Grandi, G. Delle Donne, P. Leocata, D. Trovato

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Oral cancer is the sixth most common malignancy in developed countries, representing almost 3% of malignant tumors. Tobacco use and alcohol consumption are well-established risk factors. However, the observation that most patients with oral cancer have not been exposed to these risk factors suggests that additional causes may promote oral carcinogenesis. A link has been suggested between human papillomavirus (HPV) and oral cavity cancer but the significance of HPV contribution to oral carcinogenesis as well as the prevalence of HPV infection in normal oral cavity mucosa remains debated.
Original languageEnglish
Pages (from-to)16-20
Number of pages5
JournalJOURNAL OF ORAL PATHOLOGY & MEDICINE
Volume41
DOIs
Publication statusPublished - 2012

Keywords

  • oral mucosa
  • papillomavirus

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