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Low-grade chronic inflammation in the relationship between insulin sensitivity and cardiovascular disease (RISC) population: associations with insulin resistance and cardiometabolic risk profile

  • Sr De Rooij
  • , G Nijpels
  • , Pm Nilsson
  • , Jj Nolan
  • , R Gabriel
  • , E Bobbioni Harsch
  • , Geltrude Mingrone
  • , Jm Dekker

Research output: Contribution to journalArticle

Abstract

Low-grade chronic inflammation has been hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by inducing insulin resistance. In the present study, we investigated associations between inflammation markers, insulin sensitivity (expressed as the ratio of the M value to the mean plasma insulin concentrations measured during the final 40 min of the clamp [M/I]), and a range of cardiometabolic risk factors in a large, healthy population.
Original languageEnglish
Pages (from-to)1295-1301
Number of pages7
JournalDiabetes Care
Volume32
DOIs
Publication statusPublished - 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Adult
  • Alcohol Drinking
  • Cardiovascular Diseases
  • Cohort Studies
  • Europe
  • Female
  • Heart Diseases
  • Humans
  • Inflammation
  • Insulin Resistance
  • Leukocyte Count
  • Life Style
  • Male
  • Metabolic Diseases
  • Middle Aged
  • Regression Analysis
  • Risk Factors
  • Smoking

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