Limonoids: Advances in Extraction, Characterization, and Applications

F. R. Saber; H. Salehi; M. A. Khallaf; K. Rizwan; M. Gouda; S. Ahmed; G. Zengin; Leilei Zhang; J. Rakmai; E. Secomandi; Luigi Lucini; J. Simal-Gandara

doi:10.1080/87559129.2025.2456494

Limonoids: Advances in Extraction, Characterization, and Applications

F. R. Saber^*
, H. Salehi
, M. A. Khallaf
, K. Rizwan
, M. Gouda
, S. Ahmed
, G. Zengin
, Leilei Zhang
, J. Rakmai
, E. Secomandi
, Luigi Lucini^*
, J. Simal-Gandara^*

^*Corresponding author

University of Sahiwal
National Research Center
Zhejiang University
Selcuk University
Kasetsart University
University of Vigo

Research output: Contribution to journal › Meeting Abstract

Abstract

Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.

Original language	English
Pages (from-to)	1-62
Number of pages	62
Journal	Food Reviews International
Issue number	N/A
DOIs	https://doi.org/10.1080/87559129.2025.2456494
Publication status	Published - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 2 Zero Hunger

All Science Journal Classification (ASJC) codes

Food Science
General Chemical Engineering

Keywords

Limonoids
extraction
food industry
formulations
phytochemistry
spectroscopy

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10.1080/87559129.2025.2456494

Cite this

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title = "Limonoids: Advances in Extraction, Characterization, and Applications",

abstract = "Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.",

keywords = "Limonoids, extraction, food industry, formulations, phytochemistry, spectroscopy, Limonoids, extraction, food industry, formulations, phytochemistry, spectroscopy",

author = "Saber, \{F. R.\} and H. Salehi and Khallaf, \{M. A.\} and K. Rizwan and M. Gouda and S. Ahmed and G. Zengin and Leilei Zhang and J. Rakmai and E. Secomandi and Luigi Lucini and J. Simal-Gandara",

year = "2025",

doi = "10.1080/87559129.2025.2456494",

language = "English",

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journal = "Food Reviews International",

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AU - Saber, F. R.

AU - Salehi, H.

AU - Khallaf, M. A.

AU - Rizwan, K.

AU - Gouda, M.

AU - Ahmed, S.

AU - Zengin, G.

AU - Zhang, Leilei

AU - Rakmai, J.

AU - Secomandi, E.

AU - Lucini, Luigi

AU - Simal-Gandara, J.

PY - 2025

Y1 - 2025

N2 - Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.

AB - Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.

KW - Limonoids

KW - extraction

KW - food industry

KW - formulations

KW - phytochemistry

KW - spectroscopy

KW - Limonoids

KW - extraction

KW - food industry

KW - formulations

KW - phytochemistry

KW - spectroscopy

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DO - 10.1080/87559129.2025.2456494

M3 - Meeting Abstract

SN - 8755-9129

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JO - Food Reviews International

JF - Food Reviews International

IS - N/A

ER -

Limonoids: Advances in Extraction, Characterization, and Applications

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

Keywords

Access to Document

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