Levosimendan in two neonates with ischemic heart failure
and pulmonary hypertension

Maria Pia De Carolis; Marco Piastra; Iliana Bersani; Manuela Pardeo; Eleonora Stival; Alessia Tempera; Costantino Romagnoli; Giorgio Conti; Gabriella De Rosa

Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension

Maria Pia De Carolis
, Marco Piastra
, Iliana Bersani
, Manuela Pardeo
, Eleonora Stival
, Alessia Tempera
, Costantino Romagnoli
, Giorgio Conti
, Gabriella De Rosa

Research output: Contribution to journal › Article

Abstract

We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.

Original language	English
Pages (from-to)	201-205
Number of pages	5
Journal	Neonatology
Publication status	Published - 2011

Keywords

ISCHEMIC HEART FAILURE

Cite this

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title = "Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension",

abstract = "We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.",

keywords = "ISCHEMIC HEART FAILURE, ISCHEMIC HEART FAILURE",

author = "\{De Carolis\}, \{Maria Pia\} and Marco Piastra and Iliana Bersani and Manuela Pardeo and Eleonora Stival and Alessia Tempera and Costantino Romagnoli and Giorgio Conti and \{De Rosa\}, Gabriella",

year = "2011",

language = "English",

pages = "201--205",

journal = "Neonatology",

issn = "1661-7800",

publisher = "S. Karger AG",

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TY - JOUR

T1 - Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension

AU - De Carolis, Maria Pia

AU - Piastra, Marco

AU - Bersani, Iliana

AU - Pardeo, Manuela

AU - Stival, Eleonora

AU - Tempera, Alessia

AU - Romagnoli, Costantino

AU - Conti, Giorgio

AU - De Rosa, Gabriella

PY - 2011

Y1 - 2011

N2 - We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.

AB - We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.

KW - ISCHEMIC HEART FAILURE

UR - http://hdl.handle.net/10807/3819

M3 - Article

SN - 1661-7800

SP - 201

EP - 205

JO - Neonatology

JF - Neonatology

ER -

Levosimendan in two neonates with ischemic heart failure and pulmonary hypertension

Abstract

Keywords

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