L'editing genetico: una sfida (anche) normativa

Translated title of the contribution: [Autom. eng. transl.] Gene editing: a (also) normative challenge

Research output: Contribution to journalArticle

Abstract

[Autom. eng. transl.] Modern gene editing techniques make it possible to manipulate the human genome in order to introduce, replace or modify a DNA sequence. Such manipulations may involve somatic cells, gametes or embryos. With regard, in particular, to the clinical use of gene manipulation on gametes and embryos destined for implantation, it does not seem, at least at the present stage, that these are practices free from risks for human health: so that they do not no therapeutic purpose can be recognized. When, however, such methods have reached an adequate level of safety for human health, it will well be possible to use them to correct genetic mutations causing serious diseases. However, the possibility that gene editing is also used in order to enhance the individual genetic makeup cannot be excluded: in such a way as to redesign it, selecting the desired physical and mental characteristics. This could lead to a dangerous transition from a negative to a positive eugenics, due to the difficulty of drawing a clear distinction between the concept of therapy and that of enhancement. Given these medical premises, the contribution intends to reflect on the possible criminal relevance of gene-manipulation conducts in the light of the current regulatory framework, as well as in the perspective of lege ferenda.
Translated title of the contribution[Autom. eng. transl.] Gene editing: a (also) normative challenge
Original languageItalian
Pages (from-to)1309-1318
JournalRIVISTA ITALIANA DI MEDICINA LEGALE E DEL DIRITTO IN CAMPO SANITARIO
Publication statusPublished - 2019

Keywords

  • CRISPR/Cas-9
  • editing genetico
  • eugenetica
  • manipolazione genetica
  • procreazione medicalmente assistita.

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