La medicina difensiva nella sperimentazione clinica

[Autom. eng. transl.] Research and experimental practice make it possible to perfect previous discoveries and medical knowledge, to improve treatment and reduce risk margins, but to open up new unforeseen and uncontrollable possibilities of risk. It therefore seems likely, both for the increasing diffusion of defensive medicine in all clinical practice, and for the specific and additional risks determined by experimental treatments, that in the design, in the conduction but also in the evaluation of the testing protocols, procedures or procedures are adopted. defensive medicine behaviors. Considering the aspect of patient safety in the trials, many choices, although originating from reasons of defensive medicine can be advantageous for patients, therefore they must be considered positively, even if they penalize the research budget. As regards, instead, the aspect of information and decision, the value of responsibility, together with that of autonomy, of the participating subjects should be considered adequately, for which the contents of the information should, first of all, be objectively relevant to allow you to really choose without the imposition of mandatory conditions (dictated inter alia by non-clinical reasons), more suited to the stipulation of a contract than to a fiduciary agreement of collaboration and alliance between medical researcher and patient subject of experimentation .