Isoniazid-induced pure red cell aplasia in two siblings

G. L. Marseglia; Franco Locatelli

doi:10.1016/s0022-3476(98)70330-0

Isoniazid-induced pure red cell aplasia in two siblings

G. L. Marseglia, Franco Locatelli

University of Pavia

Research output: Contribution to journal › Article

Abstract

Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused Ly PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.

Original language	English
Pages (from-to)	898-900
Number of pages	3
Journal	THE JOURNAL OF PEDIATRICS
Volume	132
DOIs	https://doi.org/10.1016/s0022-3476(98)70330-0
Publication status	Published - 1998

Keywords

Isoniazid / adverse effects

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10.1016/s0022-3476(98)70330-0

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@article{a2b57aeca2254ef5ad24e1bb4643255c,

title = "Isoniazid-induced pure red cell aplasia in two siblings",

abstract = "Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused Ly PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.",

keywords = "Isoniazid / adverse effects, Isoniazid / adverse effects",

author = "Marseglia, {G. L.} and Franco Locatelli",

year = "1998",

doi = "10.1016/s0022-3476(98)70330-0",

language = "English",

volume = "132",

pages = "898--900",

journal = "THE JOURNAL OF PEDIATRICS",

issn = "0022-3476",

publisher = "New York NY: Elsevier St. Louis Mo.: C.V. Mosby",

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TY - JOUR

T1 - Isoniazid-induced pure red cell aplasia in two siblings

AU - Marseglia, G. L.

AU - Locatelli, Franco

PY - 1998

Y1 - 1998

N2 - Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused Ly PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.

AB - Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused Ly PRCA during administration of isoniazid. On discontinuation of isoniazid, the anemia resolved rapidly. PRCA should be considered as a possible cause of unexplained anemia during isoniazid therapy in children.

KW - Isoniazid / adverse effects

UR - http://hdl.handle.net/10807/264717

U2 - 10.1016/s0022-3476(98)70330-0

DO - 10.1016/s0022-3476(98)70330-0

M3 - Article

SN - 0022-3476

VL - 132

SP - 898

EP - 900

JO - THE JOURNAL OF PEDIATRICS

JF - THE JOURNAL OF PEDIATRICS

ER -

Isoniazid-induced pure red cell aplasia in two siblings

Abstract

Keywords

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