Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

Gustavo Savino; Remo Battendieri; Andrea Siniscalco; Erika Mandara'; Antonino Mule'; Gianluigi Petrone; Salvatore Traina; Monica Riso

doi:10.1007/s00296-014-3054-7

Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

Gustavo Savino
, Remo Battendieri
, Andrea Siniscalco
, Erika Mandara'
, Antonino Mule'
, Gianluigi Petrone
, Salvatore Traina
, Monica Riso

Research output: Contribution to journal › Article

12 Citations (Scopus)

Abstract

We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.

Original language	English
Pages (from-to)	183-188
Number of pages	6
Journal	Rheumatology International
Volume	35
DOIs	https://doi.org/10.1007/s00296-014-3054-7
Publication status	Published - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

idiopathic orbital inflammatory syndrome:

Access to Document

10.1007/s00296-014-3054-7

Cite this

@article{e2fa5270e2f645cdad83ab1078dfb16e,

title = "Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports",

abstract = "We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.",

keywords = "idiopathic orbital inflammatory syndrome:, idiopathic orbital inflammatory syndrome:",

author = "Gustavo Savino and Remo Battendieri and Andrea Siniscalco and Erika Mandara' and Antonino Mule' and Gianluigi Petrone and Salvatore Traina and Monica Riso",

year = "2015",

doi = "10.1007/s00296-014-3054-7",

language = "English",

volume = "35",

pages = "183--188",

journal = "Rheumatology International",

issn = "0172-8172",

publisher = "Springer Science and Business Media Deutschland GmbH",

}

TY - JOUR

T1 - Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

AU - Savino, Gustavo

AU - Battendieri, Remo

AU - Siniscalco, Andrea

AU - Mandara', Erika

AU - Mule', Antonino

AU - Petrone, Gianluigi

AU - Traina, Salvatore

AU - Riso, Monica

PY - 2015

Y1 - 2015

N2 - We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.

AB - We report a case of a 66-year-old Caucasian female with a diagnosis of idiopathic orbital inflammatory disease (OID) refractory to azathioprine therapy. The coexistence of diabetes mellitus represented a relative contraindication to chronic prednisone use. After two infusions of rituximab, a chimeric anti-CD20+ antibody, ophthalmic signs and symptoms remarkably improved. To our knowledge, this is the first case of idiopathic OID successfully treated with rituximab.

KW - idiopathic orbital inflammatory syndrome:

UR - http://hdl.handle.net/10807/70295

U2 - 10.1007/s00296-014-3054-7

DO - 10.1007/s00296-014-3054-7

M3 - Article

SN - 0172-8172

VL - 35

SP - 183

EP - 188

JO - Rheumatology International

JF - Rheumatology International

ER -

Intraorbital injection of Rituximab in idiopathic orbital inflammatory syndrome: case reports

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this