Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report

Gabriella Macchia; Guido Costamagna; Alessio Giuseppe Morganti; Massimiliano Mutignani; Felice Giuliante; Gennaro Clemente; Francesco Deodato; Daniela Smaniotto; Gian Carlo Mattiucci; Giuseppina Sallustio; Vincenzo Valentini; Gennaro Nuzzo; Numa Cellini

doi:10.1016/j.dld.2004.07.022

Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report

Gabriella Macchia
, Guido Costamagna
, Alessio Giuseppe Morganti
, Massimiliano Mutignani
, Felice Giuliante
, Gennaro Clemente
, Francesco Deodato
, Daniela Smaniotto
, Gian Carlo Mattiucci
, Giuseppina Sallustio
, Vincenzo Valentini
, Gennaro Nuzzo
, Numa Cellini

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A 46-year-old female patient, with mild cholestasis by a large papillary cholangiocarcinoma involving the left hepatic duct, received intralummal brachytherapy (50 Gy at 1 cm from the source axis) with the aim to relieve biliary obstruction without stent positioning. The patient presented with haemobilia and vegetant lesions in the left main biliary duct, and thus she had a high risk of early stent obstruction. Eighteen months after the treatment the patient presented tumour progression in the controlateral hepatic lobe, but had a patent left hepatic duct, without signs of cholestasis and/or cholangitis. Based on this and other published reports, intraluminal brachytherapy may be tested in a setting different from standard setting with the aim to safely palliate jaundice in patients with intraductal tumour growth in the biliary tract.

Original language	English
Pages (from-to)	615-618
Number of pages	4
Journal	Digestive and Liver Disease
Volume	37
DOIs	https://doi.org/10.1016/j.dld.2004.07.022
Publication status	Published - 2005

Keywords

Brachytherapy
Cholangiocarcinoma
Intrahepatic cholangiocarcinoma
Intraluminal brachytherapy
Papillary cholangiocarcinoma

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10.1016/j.dld.2004.07.022

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Macchia, G., Costamagna, G., Morganti, A. G., Mutignani, M., Giuliante, F., Clemente, G., Deodato, F., Smaniotto, D., Mattiucci, G. C., Sallustio, G., Valentini, V., Nuzzo, G., & Cellini, N. (2005). Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report. Digestive and Liver Disease, 37, 615-618. https://doi.org/10.1016/j.dld.2004.07.022

@article{11a7c1a815f8419b87ff027e0a91a39e,

title = "Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report",

abstract = "A 46-year-old female patient, with mild cholestasis by a large papillary cholangiocarcinoma involving the left hepatic duct, received intralummal brachytherapy (50 Gy at 1 cm from the source axis) with the aim to relieve biliary obstruction without stent positioning. The patient presented with haemobilia and vegetant lesions in the left main biliary duct, and thus she had a high risk of early stent obstruction. Eighteen months after the treatment the patient presented tumour progression in the controlateral hepatic lobe, but had a patent left hepatic duct, without signs of cholestasis and/or cholangitis. Based on this and other published reports, intraluminal brachytherapy may be tested in a setting different from standard setting with the aim to safely palliate jaundice in patients with intraductal tumour growth in the biliary tract.",

keywords = "Brachytherapy, Cholangiocarcinoma, Intrahepatic cholangiocarcinoma, Intraluminal brachytherapy, Papillary cholangiocarcinoma, Brachytherapy, Cholangiocarcinoma, Intrahepatic cholangiocarcinoma, Intraluminal brachytherapy, Papillary cholangiocarcinoma",

author = "Gabriella Macchia and Guido Costamagna and Morganti, \{Alessio Giuseppe\} and Massimiliano Mutignani and Felice Giuliante and Gennaro Clemente and Francesco Deodato and Daniela Smaniotto and Mattiucci, \{Gian Carlo\} and Giuseppina Sallustio and Vincenzo Valentini and Gennaro Nuzzo and Numa Cellini",

year = "2005",

doi = "10.1016/j.dld.2004.07.022",

language = "English",

volume = "37",

pages = "615--618",

journal = "Digestive and Liver Disease",

issn = "1590-8658",

}

Macchia, G, Costamagna, G, Morganti, AG, Mutignani, M, Giuliante, F, Clemente, G, Deodato, F, Smaniotto, D, Mattiucci, GC, Sallustio, G, Valentini, V, Nuzzo, G & Cellini, N 2005, 'Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report', Digestive and Liver Disease, vol. 37, pp. 615-618. https://doi.org/10.1016/j.dld.2004.07.022

TY - JOUR

T1 - Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report

AU - Macchia, Gabriella

AU - Costamagna, Guido

AU - Morganti, Alessio Giuseppe

AU - Mutignani, Massimiliano

AU - Giuliante, Felice

AU - Clemente, Gennaro

AU - Deodato, Francesco

AU - Smaniotto, Daniela

AU - Mattiucci, Gian Carlo

AU - Sallustio, Giuseppina

AU - Valentini, Vincenzo

AU - Nuzzo, Gennaro

AU - Cellini, Numa

PY - 2005

Y1 - 2005

N2 - A 46-year-old female patient, with mild cholestasis by a large papillary cholangiocarcinoma involving the left hepatic duct, received intralummal brachytherapy (50 Gy at 1 cm from the source axis) with the aim to relieve biliary obstruction without stent positioning. The patient presented with haemobilia and vegetant lesions in the left main biliary duct, and thus she had a high risk of early stent obstruction. Eighteen months after the treatment the patient presented tumour progression in the controlateral hepatic lobe, but had a patent left hepatic duct, without signs of cholestasis and/or cholangitis. Based on this and other published reports, intraluminal brachytherapy may be tested in a setting different from standard setting with the aim to safely palliate jaundice in patients with intraductal tumour growth in the biliary tract.

AB - A 46-year-old female patient, with mild cholestasis by a large papillary cholangiocarcinoma involving the left hepatic duct, received intralummal brachytherapy (50 Gy at 1 cm from the source axis) with the aim to relieve biliary obstruction without stent positioning. The patient presented with haemobilia and vegetant lesions in the left main biliary duct, and thus she had a high risk of early stent obstruction. Eighteen months after the treatment the patient presented tumour progression in the controlateral hepatic lobe, but had a patent left hepatic duct, without signs of cholestasis and/or cholangitis. Based on this and other published reports, intraluminal brachytherapy may be tested in a setting different from standard setting with the aim to safely palliate jaundice in patients with intraductal tumour growth in the biliary tract.

KW - Brachytherapy

KW - Cholangiocarcinoma

KW - Intrahepatic cholangiocarcinoma

KW - Intraluminal brachytherapy

KW - Papillary cholangiocarcinoma

KW - Brachytherapy

KW - Cholangiocarcinoma

KW - Intrahepatic cholangiocarcinoma

KW - Intraluminal brachytherapy

KW - Papillary cholangiocarcinoma

UR - http://hdl.handle.net/10807/14556

U2 - 10.1016/j.dld.2004.07.022

DO - 10.1016/j.dld.2004.07.022

M3 - Article

SN - 1590-8658

VL - 37

SP - 615

EP - 618

JO - Digestive and Liver Disease

JF - Digestive and Liver Disease

ER -

Intraluminal brachytherapy without stenting in intrahepatic papillary cholangiocarcinoma: a case report

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