Intracranial neuromuscular choristoma: Report of a case with literature review

Antonella Coli, Gianpiero Tamburrini, Mariangela Novello, Libero Lauriola, Manila Antonelli, Felice Giangaspero

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3-year-old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.
Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalNeuropathology
Volume37
DOIs
Publication statusPublished - 2017

Keywords

  • Choristoma, cranial nerves, neural crest, neuromuscular hamartoma, skeletal muscle

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