Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention

Italo Porto; Luigi Marzio Biasucci; Giovanni Luigi De Maria; Antonio Maria Leone; Giampaolo Niccoli; Francesco Burzotta; Carlo Trani; Alessandra Tritarelli; Rocco Vergallo; Giovanna Liuzzo; Filippo Crea

doi:10.1093/eurheartj/ehs065

Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention

Italo Porto, Luigi Marzio Biasucci, Giovanni Luigi De Maria, Antonio Maria Leone, Giampaolo Niccoli, Francesco Burzotta, Carlo Trani, Alessandra Tritarelli, Rocco Vergallo, Giovanna Liuzzo, Filippo Crea

Research output: Contribution to journal › Article

Abstract

Microparticles (MP) are cell-derived fragments known to be increased in the blood of patients with acute coronary syndromes. We aimed to assess, in ST elevation myocardial infarction (STEMI), the systemic and local (in the culprit coronary artery) levels of platelet-derived MP (PMP, CD42+CD31+) and endothelial-derived MP (EMP, CD42-CD31+) and their relation to indexes of microvascular obstruction (MVO).

Original language	English
Pages (from-to)	2928-2938
Number of pages	11
Journal	European Heart Journal
Volume	33
DOIs	https://doi.org/10.1093/eurheartj/ehs065
Publication status	Published - 2012

Keywords

Analysis of Variance
Blood Platelets
Cell-Derived Microparticles
Coronary Occlusion
Coronary Thrombosis
Endothelium, Vascular
Female
Humans
Male
Microcirculation
Microvessels
Middle Aged
Multivariate Analysis
Myocardial Infarction
Myocardial Reperfusion
Percutaneous Coronary Intervention
Prospective Studies

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10.1093/eurheartj/ehs065

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Porto, I., Biasucci, L. M., De Maria, G. L., Leone, A. M., Niccoli, G., Burzotta, F., Trani, C., Tritarelli, A., Vergallo, R., Liuzzo, G., & Crea, F. (2012). Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention. European Heart Journal, 33, 2928-2938. https://doi.org/10.1093/eurheartj/ehs065

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title = "Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention",

abstract = "Microparticles (MP) are cell-derived fragments known to be increased in the blood of patients with acute coronary syndromes. We aimed to assess, in ST elevation myocardial infarction (STEMI), the systemic and local (in the culprit coronary artery) levels of platelet-derived MP (PMP, CD42+CD31+) and endothelial-derived MP (EMP, CD42-CD31+) and their relation to indexes of microvascular obstruction (MVO).",

keywords = "Analysis of Variance, Blood Platelets, Cell-Derived Microparticles, Coronary Occlusion, Coronary Thrombosis, Endothelium, Vascular, Female, Humans, Male, Microcirculation, Microvessels, Middle Aged, Multivariate Analysis, Myocardial Infarction, Myocardial Reperfusion, Percutaneous Coronary Intervention, Prospective Studies, Analysis of Variance, Blood Platelets, Cell-Derived Microparticles, Coronary Occlusion, Coronary Thrombosis, Endothelium, Vascular, Female, Humans, Male, Microcirculation, Microvessels, Middle Aged, Multivariate Analysis, Myocardial Infarction, Myocardial Reperfusion, Percutaneous Coronary Intervention, Prospective Studies",

author = "Italo Porto and Biasucci, {Luigi Marzio} and {De Maria}, {Giovanni Luigi} and Leone, {Antonio Maria} and Giampaolo Niccoli and Francesco Burzotta and Carlo Trani and Alessandra Tritarelli and Rocco Vergallo and Giovanna Liuzzo and Filippo Crea",

year = "2012",

doi = "10.1093/eurheartj/ehs065",

language = "English",

volume = "33",

pages = "2928--2938",

journal = "European Heart Journal",

issn = "0195-668X",

publisher = "Oxford University Press",

}

Porto, I, Biasucci, LM, De Maria, GL, Leone, AM, Niccoli, G, Burzotta, F , Trani, C, Tritarelli, A, Vergallo, R, Liuzzo, G & Crea, F 2012, 'Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention', European Heart Journal, vol. 33, pp. 2928-2938. https://doi.org/10.1093/eurheartj/ehs065

TY - JOUR

T1 - Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention

AU - Porto, Italo

AU - Biasucci, Luigi Marzio

AU - De Maria, Giovanni Luigi

AU - Leone, Antonio Maria

AU - Niccoli, Giampaolo

AU - Burzotta, Francesco

AU - Trani, Carlo

AU - Tritarelli, Alessandra

AU - Vergallo, Rocco

AU - Liuzzo, Giovanna

AU - Crea, Filippo

PY - 2012

Y1 - 2012

N2 - Microparticles (MP) are cell-derived fragments known to be increased in the blood of patients with acute coronary syndromes. We aimed to assess, in ST elevation myocardial infarction (STEMI), the systemic and local (in the culprit coronary artery) levels of platelet-derived MP (PMP, CD42+CD31+) and endothelial-derived MP (EMP, CD42-CD31+) and their relation to indexes of microvascular obstruction (MVO).

AB - Microparticles (MP) are cell-derived fragments known to be increased in the blood of patients with acute coronary syndromes. We aimed to assess, in ST elevation myocardial infarction (STEMI), the systemic and local (in the culprit coronary artery) levels of platelet-derived MP (PMP, CD42+CD31+) and endothelial-derived MP (EMP, CD42-CD31+) and their relation to indexes of microvascular obstruction (MVO).

KW - Analysis of Variance

KW - Blood Platelets

KW - Cell-Derived Microparticles

KW - Coronary Occlusion

KW - Coronary Thrombosis

KW - Endothelium, Vascular

KW - Female

KW - Humans

KW - Male

KW - Microcirculation

KW - Microvessels

KW - Middle Aged

KW - Multivariate Analysis

KW - Myocardial Infarction

KW - Myocardial Reperfusion

KW - Percutaneous Coronary Intervention

KW - Prospective Studies

KW - Analysis of Variance

KW - Blood Platelets

KW - Cell-Derived Microparticles

KW - Coronary Occlusion

KW - Coronary Thrombosis

KW - Endothelium, Vascular

KW - Female

KW - Humans

KW - Male

KW - Microcirculation

KW - Microvessels

KW - Middle Aged

KW - Multivariate Analysis

KW - Myocardial Infarction

KW - Myocardial Reperfusion

KW - Percutaneous Coronary Intervention

KW - Prospective Studies

UR - http://hdl.handle.net/10807/66900

U2 - 10.1093/eurheartj/ehs065

DO - 10.1093/eurheartj/ehs065

M3 - Article

SN - 0195-668X

VL - 33

SP - 2928

EP - 2938

JO - European Heart Journal

JF - European Heart Journal

ER -

Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention

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Keywords

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