Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

Stefania Boccia; Ida Torre; Lidia Santarpia; Carmela Iervolino; Concetta Del Piano; Anna Puggina; Roberta Pastorino; Miroslav Dragic; Rosarita Amore; Tonia Borriello; Raffaele Palladino; Francesca Pennino; Franco Contaldo; Fabrizio Pasanisi

doi:10.1016/j.clnu.2016.09.028

Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

Stefania Boccia
, Ida Torre
, Lidia Santarpia
, Carmela Iervolino
, Concetta Del Piano
, Anna Puggina
, Roberta Pastorino
, Miroslav Dragic
, Rosarita Amore
, Tonia Borriello
, Raffaele Palladino
, Francesca Pennino
, Franco Contaldo
, Fabrizio Pasanisi

University of Naples Federico II

Research output: Contribution to journal › Article

12 Citations (Scopus)

Abstract

Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.

Original language	English
Pages (from-to)	1707-1709
Number of pages	3
Journal	Clinical Nutrition
DOIs	https://doi.org/10.1016/j.clnu.2016.09.028
Publication status	Published - 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Critical Care and Intensive Care Medicine
Intestinal microbiota
Nutrition and Dietetics
Short Bowel Syndrome

Access to Document

10.1016/j.clnu.2016.09.028

Cite this

Boccia, S., Torre, I., Santarpia, L., Iervolino, C., Del Piano, C., Puggina, A., Pastorino, R., Dragic, M., Amore, R., Borriello, T., Palladino, R., Pennino, F., Contaldo, F., & Pasanisi, F. (2017). Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study. Clinical Nutrition, 1707-1709. https://doi.org/10.1016/j.clnu.2016.09.028

@article{3fda150a9112407488f19733b4f07618,

title = "Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study",

abstract = "Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.",

keywords = "Critical Care and Intensive Care Medicine, Intestinal microbiota, Nutrition and Dietetics, Short Bowel Syndrome, Critical Care and Intensive Care Medicine, Intestinal microbiota, Nutrition and Dietetics, Short Bowel Syndrome",

author = "Stefania Boccia and Ida Torre and Lidia Santarpia and Carmela Iervolino and \{Del Piano\}, Concetta and Anna Puggina and Roberta Pastorino and Miroslav Dragic and Rosarita Amore and Tonia Borriello and Raffaele Palladino and Francesca Pennino and Franco Contaldo and Fabrizio Pasanisi",

year = "2017",

doi = "10.1016/j.clnu.2016.09.028",

language = "English",

pages = "1707--1709",

journal = "Clinical Nutrition",

issn = "0261-5614",

publisher = "Churchill Livingstone",

}

TY - JOUR

T1 - Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

AU - Boccia, Stefania

AU - Torre, Ida

AU - Santarpia, Lidia

AU - Iervolino, Carmela

AU - Del Piano, Concetta

AU - Puggina, Anna

AU - Pastorino, Roberta

AU - Dragic, Miroslav

AU - Amore, Rosarita

AU - Borriello, Tonia

AU - Palladino, Raffaele

AU - Pennino, Francesca

AU - Contaldo, Franco

AU - Pasanisi, Fabrizio

PY - 2017

Y1 - 2017

N2 - Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.

AB - Introduction: Intestinal bacterial flora plays a central role in human intestinal health and disease. Short Bowel Syndrome (SBS), a clinical condition deriving from extensive bowel resections, influence intestinal microbiota (IM) composition in order to reach a new metabolic balance. Little is known about IM in adult patients after wide intestinal resections. Material and methods: Fecal samples from 12 SBS patients and 16 controls were analyzed in their microbial profile by using both culture-dependent method and quantitative Real-Time PCR (qRT-PCR). Results: The two methods revealed significant lower concentrations of . Bacteroidetes (p-value = .02), . Firmicutes (p-value = .05), . Bifidobacterium (p-value < .01), and . Methanobrevibacter Smithii (p-value = .04) in SBS patients than controls. Conclusions: The significantly different fecal microbiome in SBS patients compared with healthy controls could open new perspectives on the care of their intestinal functions.

KW - Critical Care and Intensive Care Medicine

KW - Intestinal microbiota

KW - Nutrition and Dietetics

KW - Short Bowel Syndrome

KW - Critical Care and Intensive Care Medicine

KW - Intestinal microbiota

KW - Nutrition and Dietetics

KW - Short Bowel Syndrome

UR - http://hdl.handle.net/10807/92929

UR - http://www.elsevier-international.com/journals/clnu/

U2 - 10.1016/j.clnu.2016.09.028

DO - 10.1016/j.clnu.2016.09.028

M3 - Article

SN - 0261-5614

SP - 1707

EP - 1709

JO - Clinical Nutrition

JF - Clinical Nutrition

ER -

Intestinal microbiota in adult patients with Short Bowel Syndrome: Preliminary results from a pilot study

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this