TY - JOUR
T1 - Interventional Oncology and Immuno-Oncology: Current Challenges and Future Trends
AU - Posa, Alessandro
AU - Contegiacomo, Andrea
AU - Ponziani, Francesca Romana
AU - Punzi, Ernesto
AU - Mazza, Giulia
AU - Scrofani, Annarita
AU - Pompili, Maurizio
AU - Goldberg, Shraga Nahum
AU - Natale, Luigi
AU - Gasbarrini, Antonio
AU - Sala, Evis
AU - Iezzi, Roberto
PY - 2023
Y1 - 2023
N2 - Personalized cancer treatments help to deliver tailored and biologically driven therapies for cancer patients. Interventional oncology techniques are able to treat malignancies in a locoregional fashion, with a variety of mechanisms of action leading to tumor necrosis. Tumor destruction determines a great availability of tumor antigens that can be recognized by the immune system, potentially triggering an immune response. The advent of immunotherapy in cancer care, with the introduction of specific immune checkpoint inhibitors, has led to the investigation of the synergy of these drugs when used in combination with interventional oncology treatments. The aim of this paper is to review the most recent advances in the field of interventional oncology locoregional treatments and their interactions with immunotherapy.
AB - Personalized cancer treatments help to deliver tailored and biologically driven therapies for cancer patients. Interventional oncology techniques are able to treat malignancies in a locoregional fashion, with a variety of mechanisms of action leading to tumor necrosis. Tumor destruction determines a great availability of tumor antigens that can be recognized by the immune system, potentially triggering an immune response. The advent of immunotherapy in cancer care, with the introduction of specific immune checkpoint inhibitors, has led to the investigation of the synergy of these drugs when used in combination with interventional oncology treatments. The aim of this paper is to review the most recent advances in the field of interventional oncology locoregional treatments and their interactions with immunotherapy.
KW - ablation
KW - immune checkpoint inhibitors
KW - personalized medicine
KW - interventional oncology
KW - immunotherapy
KW - ablation
KW - immune checkpoint inhibitors
KW - personalized medicine
KW - interventional oncology
KW - immunotherapy
UR - http://hdl.handle.net/10807/240223
U2 - 10.3390/ijms24087344
DO - 10.3390/ijms24087344
M3 - Article
SN - 1422-0067
VL - 24
SP - 7344-N/A
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
ER -
