Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score

Andrea De Luca; Simona Di Giambenedetto; R Maserati; N Gianotti; P Narciso; A Antinori; G Di Perri; Mcf Prosperi; F Baldanti; V Micheli; M Zazzi; Cf Perno; Mm Santoro

doi:10.3851/IMP1799

Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score

Andrea De Luca
, Simona Di Giambenedetto
, R Maserati
, N Gianotti
, P Narciso
, A Antinori
, G Di Perri
, Mcf Prosperi
, F Baldanti
, V Micheli
, M Zazzi
, Cf Perno
, Mm Santoro

Azienda Ospedaliera Universitaria Senese

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

There is not yet consensus on interpretation of genotypic HIV-1 resistance to darunavir (DRV). We validated existing rules and a newly derived score.

Original language	English
Pages (from-to)	489-497
Number of pages	9
Journal	Antiviral Therapy
Volume	16
Issue number	4
DOIs	https://doi.org/10.3851/IMP1799
Publication status	Published - 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Algorithms
Anti-HIV Agents
Combination
Drug Resistance
Drug Therapy
Genotype
HIV Infections
HIV Protease Inhibitors
HIV-1
Humans
Microbial Sensitivity Tests
Predictive Value of Tests
Ritonavir
Sulfonamides
Treatment Outcome
Viral

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10.3851/IMP1799

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De Luca, A., Di Giambenedetto, S., Maserati, R., Gianotti, N., Narciso, P., Antinori, A., Di Perri, G., Prosperi, M., Baldanti, F., Micheli, V., Zazzi, M., Perno, C., & Santoro, M. (2011). Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score. Antiviral Therapy, 16(4), 489-497. https://doi.org/10.3851/IMP1799

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title = "Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score",

abstract = "There is not yet consensus on interpretation of genotypic HIV-1 resistance to darunavir (DRV). We validated existing rules and a newly derived score.",

keywords = "Algorithms, Anti-HIV Agents, Combination, Drug Resistance, Drug Therapy, Genotype, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Microbial Sensitivity Tests, Predictive Value of Tests, Ritonavir, Sulfonamides, Treatment Outcome, Viral, Algorithms, Anti-HIV Agents, Combination, Drug Resistance, Drug Therapy, Genotype, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Microbial Sensitivity Tests, Predictive Value of Tests, Ritonavir, Sulfonamides, Treatment Outcome, Viral",

author = "\{De Luca\}, Andrea and \{Di Giambenedetto\}, Simona and R Maserati and N Gianotti and P Narciso and A Antinori and \{Di Perri\}, G and Mcf Prosperi and F Baldanti and V Micheli and M Zazzi and Cf Perno and Mm Santoro",

year = "2011",

doi = "10.3851/IMP1799",

language = "English",

volume = "16",

pages = "489--497",

journal = "Antiviral Therapy",

issn = "1359-6535",

publisher = "Sage Publications",

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}

De Luca, A, Di Giambenedetto, S, Maserati, R, Gianotti, N, Narciso, P, Antinori, A, Di Perri, G, Prosperi, M, Baldanti, F, Micheli, V, Zazzi, M, Perno, C & Santoro, M 2011, 'Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score', Antiviral Therapy, vol. 16, no. 4, pp. 489-497. https://doi.org/10.3851/IMP1799

TY - JOUR

T1 - Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score

AU - De Luca, Andrea

AU - Di Giambenedetto, Simona

AU - Maserati, R

AU - Gianotti, N

AU - Narciso, P

AU - Antinori, A

AU - Di Perri, G

AU - Prosperi, Mcf

AU - Baldanti, F

AU - Micheli, V

AU - Zazzi, M

AU - Perno, Cf

AU - Santoro, Mm

PY - 2011

Y1 - 2011

N2 - There is not yet consensus on interpretation of genotypic HIV-1 resistance to darunavir (DRV). We validated existing rules and a newly derived score.

AB - There is not yet consensus on interpretation of genotypic HIV-1 resistance to darunavir (DRV). We validated existing rules and a newly derived score.

KW - Algorithms

KW - Anti-HIV Agents

KW - Combination

KW - Drug Resistance

KW - Drug Therapy

KW - Genotype

KW - HIV Infections

KW - HIV Protease Inhibitors

KW - HIV-1

KW - Humans

KW - Microbial Sensitivity Tests

KW - Predictive Value of Tests

KW - Ritonavir

KW - Sulfonamides

KW - Treatment Outcome

KW - Viral

KW - Algorithms

KW - Anti-HIV Agents

KW - Combination

KW - Drug Resistance

KW - Drug Therapy

KW - Genotype

KW - HIV Infections

KW - HIV Protease Inhibitors

KW - HIV-1

KW - Humans

KW - Microbial Sensitivity Tests

KW - Predictive Value of Tests

KW - Ritonavir

KW - Sulfonamides

KW - Treatment Outcome

KW - Viral

UR - https://publicatt.unicatt.it/handle/10807/6343

U2 - 10.3851/IMP1799

DO - 10.3851/IMP1799

M3 - Article

SN - 1359-6535

VL - 16

SP - 489

EP - 497

JO - Antiviral Therapy

JF - Antiviral Therapy

IS - 4

ER -

Interpretation of genotypic HIV-1 resistance to darunavir and virological response: validation of available systems and of a new score

Abstract

UN SDGs

Keywords

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