Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality

Evangelos J. Giamarellos-Bourboulis; Massimo Antonelli; Frank Bloos; Ioanna Kotsamidi; Christos Psarrakis; Konstantina Dakou; Daniel Thomas-Rüddel; Luca Montini; Josef Briegel; Georgia Damoraki; Panagiotis Koufargyris; Souzana Anisoglou; Eleni Antoniadou; Glykeria Vlachogianni; Christos Tsiantas; Matteo Masullo; Aikaterini Ioakeimidou; Eumorfia Kondili; Maria Ntaganou; Eleni Gkeka; Vassileios Papaioannou; Effie Polyzogopoulou; Armin J. Reininger; Gennaro De Pascale; Michael Kiehntopf; Eleni Mouloudi; Michael Bauer

doi:10.1016/j.ebiom.2024.105414

Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality

Evangelos J. Giamarellos-Bourboulis
, Massimo Antonelli
, Frank Bloos
, Ioanna Kotsamidi
, Christos Psarrakis
, Konstantina Dakou
, Daniel Thomas-Rüddel
, Luca Montini
, Josef Briegel
, Georgia Damoraki
, Panagiotis Koufargyris
, Souzana Anisoglou
, Eleni Antoniadou
, Glykeria Vlachogianni
, Christos Tsiantas
, Matteo Masullo
, Aikaterini Ioakeimidou
, Eumorfia Kondili
, Maria Ntaganou
, Eleni Gkeka

Vassileios Papaioannou, Effie Polyzogopoulou, Armin J. Reininger, Gennaro De Pascale, Michael Kiehntopf, Eleni Mouloudi, Michael Bauer

National and Kapodistrian University of Athens
Jena University Hospital
General Hospital “Ippokrateion”
Hellenic Institute for the Study of Sepsis
LMU Munich
Theageneio General Hospital
G. Gennimatas General Hospital
General Hospital “Aghios Dimitrios”
Aristotle University of Thessaloniki
General Hospital Asklipeion
University of Crete
Athens General Hospital
Democritus University of Thrace
Swedish Orphan Biovitrum AG (Sobi)
Friedrich Schiller University Jena

Research output: Contribution to journal › Article

Original language	English
Pages (from-to)	N/A-N/A
Journal	EBioMedicine
Volume	109
DOIs	https://doi.org/10.1016/j.ebiom.2024.105414
Publication status	Published - 2024

Keywords

CXCL9
Interferon-gamma
Macrophages
Outcome
Sepsis

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10.1016/j.ebiom.2024.105414

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Giamarellos-Bourboulis, E. J., Antonelli, M., Bloos, F., Kotsamidi, I., Psarrakis, C., Dakou, K., Thomas-Rüddel, D., Montini, L., Briegel, J., Damoraki, G., Koufargyris, P., Anisoglou, S., Antoniadou, E., Vlachogianni, G., Tsiantas, C., Masullo, M., Ioakeimidou, A., Kondili, E., Ntaganou, M., ... Bauer, M. (2024). Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality. EBioMedicine, 109, N/A-N/A. https://doi.org/10.1016/j.ebiom.2024.105414

@article{842b37a6212040b99dd6ceb7ac9f9f72,

title = "Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality",

keywords = "CXCL9, Interferon-gamma, Macrophages, Outcome, Sepsis, CXCL9, Interferon-gamma, Macrophages, Outcome, Sepsis",

author = "Giamarellos-Bourboulis, \{Evangelos J.\} and Massimo Antonelli and Frank Bloos and Ioanna Kotsamidi and Christos Psarrakis and Konstantina Dakou and Daniel Thomas-R{\"u}ddel and Luca Montini and Josef Briegel and Georgia Damoraki and Panagiotis Koufargyris and Souzana Anisoglou and Eleni Antoniadou and Glykeria Vlachogianni and Christos Tsiantas and Matteo Masullo and Aikaterini Ioakeimidou and Eumorfia Kondili and Maria Ntaganou and Eleni Gkeka and Vassileios Papaioannou and Effie Polyzogopoulou and Reininger, \{Armin J.\} and \{De Pascale\}, Gennaro and Michael Kiehntopf and Eleni Mouloudi and Michael Bauer",

year = "2024",

doi = "10.1016/j.ebiom.2024.105414",

language = "English",

volume = "109",

pages = "N/A--N/A",

journal = "EBioMedicine",

issn = "2352-3964",

publisher = "Elsevier B.V.",

}

Giamarellos-Bourboulis, EJ, Antonelli, M, Bloos, F, Kotsamidi, I, Psarrakis, C, Dakou, K, Thomas-Rüddel, D, Montini, L, Briegel, J, Damoraki, G, Koufargyris, P, Anisoglou, S, Antoniadou, E, Vlachogianni, G, Tsiantas, C, Masullo, M, Ioakeimidou, A, Kondili, E, Ntaganou, M, Gkeka, E, Papaioannou, V, Polyzogopoulou, E, Reininger, AJ, De Pascale, G, Kiehntopf, M, Mouloudi, E & Bauer, M 2024, 'Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality', EBioMedicine, vol. 109, pp. N/A-N/A. https://doi.org/10.1016/j.ebiom.2024.105414

TY - JOUR

T1 - Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality

AU - Giamarellos-Bourboulis, Evangelos J.

AU - Antonelli, Massimo

AU - Bloos, Frank

AU - Kotsamidi, Ioanna

AU - Psarrakis, Christos

AU - Dakou, Konstantina

AU - Thomas-Rüddel, Daniel

AU - Montini, Luca

AU - Briegel, Josef

AU - Damoraki, Georgia

AU - Koufargyris, Panagiotis

AU - Anisoglou, Souzana

AU - Antoniadou, Eleni

AU - Vlachogianni, Glykeria

AU - Tsiantas, Christos

AU - Masullo, Matteo

AU - Ioakeimidou, Aikaterini

AU - Kondili, Eumorfia

AU - Ntaganou, Maria

AU - Gkeka, Eleni

AU - Papaioannou, Vassileios

AU - Polyzogopoulou, Effie

AU - Reininger, Armin J.

AU - De Pascale, Gennaro

AU - Kiehntopf, Michael

AU - Mouloudi, Eleni

AU - Bauer, Michael

PY - 2024

Y1 - 2024

KW - CXCL9

KW - Interferon-gamma

KW - Macrophages

KW - Outcome

KW - Sepsis

KW - CXCL9

KW - Interferon-gamma

KW - Macrophages

KW - Outcome

KW - Sepsis

UR - http://hdl.handle.net/10807/297450

U2 - 10.1016/j.ebiom.2024.105414

DO - 10.1016/j.ebiom.2024.105414

M3 - Article

SN - 2352-3964

VL - 109

SP - N/A-N/A

JO - EBioMedicine

JF - EBioMedicine

ER -

Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality

Keywords

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