INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival

Elena Zunarelli; Nazzarena Bigiani; Giuliana Sartori; Mario Migaldi; Alessandro Sgambato; Antonio Maiorana; Alessandro Maiorana

doi:10.1097/PAT.0b013e328340bb26

INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival

Elena Zunarelli
, Nazzarena Bigiani
, Giuliana Sartori
, Mario Migaldi
, Alessandro Sgambato
, Antonio Maiorana
, Alessandro Maiorana

University of Modena and Reggio Emilia

Research output: Contribution to journal › Article

9 Citations (Scopus)

Abstract

INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ).

Original language	English
Pages (from-to)	17-23
Number of pages	7
Journal	Pathology
Volume	43
DOIs	https://doi.org/10.1097/PAT.0b013e328340bb26
Publication status	Published - 2011

Keywords

Adult
Aged
Chromosomal Proteins, Non-Histone
DNA Methylation
DNA Modification Methylases
DNA Repair Enzymes
DNA-Binding Proteins
Female
Gene Expression
Glioblastoma
Humans
Italy
Kaplan-Meier Estimate
Male
Middle Aged
Promoter Regions, Genetic
Supratentorial Neoplasms
Survival Rate
Transcription Factors
Tumor Markers, Biological
Tumor Suppressor Proteins

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10.1097/PAT.0b013e328340bb26

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title = "INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival",

abstract = "INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ).",

keywords = "Adult, Aged, Chromosomal Proteins, Non-Histone, DNA Methylation, DNA Modification Methylases, DNA Repair Enzymes, DNA-Binding Proteins, Female, Gene Expression, Glioblastoma, Humans, Italy, Kaplan-Meier Estimate, Male, Middle Aged, Promoter Regions, Genetic, Supratentorial Neoplasms, Survival Rate, Transcription Factors, Tumor Markers, Biological, Tumor Suppressor Proteins, Adult, Aged, Chromosomal Proteins, Non-Histone, DNA Methylation, DNA Modification Methylases, DNA Repair Enzymes, DNA-Binding Proteins, Female, Gene Expression, Glioblastoma, Humans, Italy, Kaplan-Meier Estimate, Male, Middle Aged, Promoter Regions, Genetic, Supratentorial Neoplasms, Survival Rate, Transcription Factors, Tumor Markers, Biological, Tumor Suppressor Proteins",

author = "Elena Zunarelli and Nazzarena Bigiani and Giuliana Sartori and Mario Migaldi and Alessandro Sgambato and Antonio Maiorana and Alessandro Maiorana",

year = "2011",

doi = "10.1097/PAT.0b013e328340bb26",

language = "English",

volume = "43",

pages = "17--23",

journal = "Pathology",

issn = "0031-3025",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival

AU - Zunarelli, Elena

AU - Bigiani, Nazzarena

AU - Sartori, Giuliana

AU - Migaldi, Mario

AU - Sgambato, Alessandro

AU - Maiorana, Antonio

AU - Maiorana, Alessandro

PY - 2011

Y1 - 2011

N2 - INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ).

AB - INI1 expression and its correlation with MGMT gene promoter methylation status and follow-up was investigated in 77 surgically removed glioblastomas then treated with radiotherapy (RT) or RT plus temozolomide (TMZ).

KW - Adult

KW - Aged

KW - Chromosomal Proteins, Non-Histone

KW - DNA Methylation

KW - DNA Modification Methylases

KW - DNA Repair Enzymes

KW - DNA-Binding Proteins

KW - Female

KW - Gene Expression

KW - Glioblastoma

KW - Humans

KW - Italy

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Promoter Regions, Genetic

KW - Supratentorial Neoplasms

KW - Survival Rate

KW - Transcription Factors

KW - Tumor Markers, Biological

KW - Tumor Suppressor Proteins

KW - Adult

KW - Aged

KW - Chromosomal Proteins, Non-Histone

KW - DNA Methylation

KW - DNA Modification Methylases

KW - DNA Repair Enzymes

KW - DNA-Binding Proteins

KW - Female

KW - Gene Expression

KW - Glioblastoma

KW - Humans

KW - Italy

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Promoter Regions, Genetic

KW - Supratentorial Neoplasms

KW - Survival Rate

KW - Transcription Factors

KW - Tumor Markers, Biological

KW - Tumor Suppressor Proteins

UR - http://hdl.handle.net/10807/5607

U2 - 10.1097/PAT.0b013e328340bb26

DO - 10.1097/PAT.0b013e328340bb26

M3 - Article

SN - 0031-3025

VL - 43

SP - 17

EP - 23

JO - Pathology

JF - Pathology

ER -

INI1 immunohistochemical expression in glioblastoma: correlation with MGMT gene promoter methylation status and patient survival

Abstract

Keywords

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