@article{d04eb4734642442c954341acf0fc008c,
title = "Increased PTPN22 Expression and Defective CREB Activation Impair Regulatory T-Cell Differentiation in Non-ST-Segment Elevation Acute Coronary Syndromes",
abstract = "Critical impairment of adaptive immune response has been observed in patients with acute coronary syndromes (ACS) with reduced expansion of regulatory T cells (Treg) and enhanced effector T-cell responsiveness, both associated with poorer outcomes.",
keywords = "dysregulation, immune system, signaling pathway, dysregulation, immune system, signaling pathway",
author = "Davide Flego and Anna Severino and Francesco Trotta and Sarassunta Ucci and Chiara Zara and Gianluca Massaro and Daniela Pedicino and Biasucci, {Luigi Marzio} and Giovanna Liuzzo and Filippo Crea",
year = "2015",
doi = "10.1016/j.jacc.2015.01.027",
language = "English",
volume = "65",
pages = "1175--1186",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 W B Saunders Company:Fulfillment Department, The Curtis Center, Independence Square West:Philadelphia, PA 19106:(800)654-2452, (215)238-7800, EMAIL:
[email protected], INTERNET: http://elsevierhealth.com, Fax: (215)238-6445",
}