Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Luca Reggiani Bonetti; Mario Migaldi; Emanuele Caredda; Alma Boninsegna Lucarelli; Maurizio Ponz De Leon; Carmela Di Gregorio; Valeria Barresi; Domenico Scannone; Silvio Danese; Achille Renato Maria Cittadini; Alessandro Sgambato

doi:10.3109/00365521.2012.694904

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Luca Reggiani Bonetti
, Mario Migaldi
, Emanuele Caredda
, Alma Boninsegna Lucarelli
, Maurizio Ponz De Leon
, Carmela Di Gregorio
, Valeria Barresi
, Domenico Scannone
, Silvio Danese
, Achille Renato Maria Cittadini
, Alessandro Sgambato

University of Modena and Reggio Emilia
University of Messina

Research output: Contribution to journal › Article

18 Citations (Scopus)

Abstract

Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

Original language	English
Pages (from-to)	1211-1217
Number of pages	7
Journal	Scandinavian Journal of Gastroenterology
Volume	47
DOIs	https://doi.org/10.3109/00365521.2012.694904
Publication status	Published - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

CD113
colo-rectal cancer

Access to Document

10.3109/00365521.2012.694904

Cite this

Reggiani Bonetti, L., Migaldi, M., Caredda, E., Boninsegna Lucarelli, A., Ponz De Leon, M., Di Gregorio, C., Barresi, V., Scannone, D., Danese, S., Cittadini, A. R. M., & Sgambato, A. (2012). Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients. Scandinavian Journal of Gastroenterology, 47, 1211-1217. https://doi.org/10.3109/00365521.2012.694904

@article{a9c02c4edf3d4070a54509f1d3a7fd5a,

title = "Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients",

abstract = "Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.",

keywords = "CD113, colo-rectal cancer, CD113, colo-rectal cancer",

author = "\{Reggiani Bonetti\}, Luca and Mario Migaldi and Emanuele Caredda and \{Boninsegna Lucarelli\}, Alma and \{Ponz De Leon\}, Maurizio and \{Di Gregorio\}, Carmela and Valeria Barresi and Domenico Scannone and Silvio Danese and Cittadini, \{Achille Renato Maria\} and Alessandro Sgambato",

year = "2012",

doi = "10.3109/00365521.2012.694904",

language = "English",

volume = "47",

pages = "1211--1217",

journal = "Scandinavian Journal of Gastroenterology",

issn = "0036-5521",

publisher = "Taylor and Francis Ltd.",

}

Reggiani Bonetti, L, Migaldi, M, Caredda, E, Boninsegna Lucarelli, A, Ponz De Leon, M, Di Gregorio, C, Barresi, V, Scannone, D, Danese, S, Cittadini, ARM & Sgambato, A 2012, 'Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients', Scandinavian Journal of Gastroenterology, vol. 47, pp. 1211-1217. https://doi.org/10.3109/00365521.2012.694904

TY - JOUR

T1 - Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

AU - Reggiani Bonetti, Luca

AU - Migaldi, Mario

AU - Caredda, Emanuele

AU - Boninsegna Lucarelli, Alma

AU - Ponz De Leon, Maurizio

AU - Di Gregorio, Carmela

AU - Barresi, Valeria

AU - Scannone, Domenico

AU - Danese, Silvio

AU - Cittadini, Achille Renato Maria

AU - Sgambato, Alessandro

PY - 2012

Y1 - 2012

N2 - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

AB - Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.

KW - CD113

KW - colo-rectal cancer

KW - CD113

KW - colo-rectal cancer

UR - http://hdl.handle.net/10807/40255

U2 - 10.3109/00365521.2012.694904

DO - 10.3109/00365521.2012.694904

M3 - Article

SN - 0036-5521

VL - 47

SP - 1211

EP - 1217

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

ER -

Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this