Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients

Alessandro Sgambato, Emanuele Caredda, Alma Boninsegna Lucarelli, Silvio Danese, Achille Renato Maria Cittadini, Luca Reggiani Bonetti, Mario Migaldi, Maurizio Ponz De Leon, Carmela Di Gregorio, Valeria Barresi

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Stage I colorectal carcinomas display a highly variable behavior which is not accurately predicted by the available prognostic markers. CD133 is considered a useful marker to identify the so-called cancer stem cells in colorectal cancers (CRCs) and its expression has been shown to have prognostic significance in CRC patients. This study aimed to verify whether immunohistochemical evaluation of CD133 might correlate with the progression risk of stage I CRC patients.
Original languageEnglish
Pages (from-to)1211-1217
Number of pages7
JournalScandinavian Journal of Gastroenterology
Volume47
DOIs
Publication statusPublished - 2012

Keywords

  • CD113
  • colo-rectal cancer

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