Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b

Antonio Alberto Zuppa, Francesco Cota, Daniele De Luca, Federica Visintini, Pierluigi De Turris, Giuseppe Gio Batta Tortorolo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Neonatal alloimmune thrombocytopenia (NAIT) is usually attributable to HPA-1a antibodies. The authors report a case of incidentally diagnosed thrombocytopenia in a small for gestational age infant. A NAIT was suspected and she was successfully treated with intravenous IgG. The direct and indirect platelet suspension immunofluorescence test (PSIFT) in maternal blood suggested alloimmunization to HPA-5b. Empiric treatment with IgG could be useful in case of clear suspect even in absence of confirmed diagnosis.
Original languageEnglish
Pages (from-to)587-591
Number of pages5
JournalPediatric Hematology and Oncology
Publication statusPublished - 2002

Keywords

  • newborn
  • thrombocytopenia

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