Incidence, clinical features and management of hypersensitivity reactions to chemotherapeutic drugs in children with cancer

Antonio Ruggiero, Silvia Triarico, Giovanna Trombatore, Andrea Battista, Riccardo Riccardi, Fabiola Dell'Acqua, Carmelo Rizzari

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Hypersensitivity reactions (HSRs) may occur in children with cancer during the use of almost all chemotherapeutic drugs. HSRs may also produce a negative impact on treatment intensity and, as a consequence, worsen patients' outcome. The aim of this review is to summarize the incidence and the clinical features of HSRs occurring in children with cancer treated with chemotherapeutic drugs and their impact on treatment efficacy, in order to outline possible adequate prevention and management strategies.
Original languageEnglish
Pages (from-to)1739-1746
Number of pages8
JournalEuropean Journal of Clinical Pharmacology
Volume69
DOIs
Publication statusPublished - 2013

Keywords

  • chemotherapeutic drugs
  • hypersensitivity

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