Abstract
Although resistance to tigecycline has been reported in surveillance studies, a very few reports described the emergence of resistance in vivo. We report two cases of patients with infections due to SHV-12 producing Klebsiella pneumoniae and K. pneumoniae carbapenemase-3 (KPC-3) producing Escherichia coli, which developed tigecycline resistance in vivo after treatment. The reported limited experience underlines the risk of occurrence of tigecycline MIC increase under treatment pressure.
| Original language | English |
|---|---|
| Pages (from-to) | 4516-4518 |
| Number of pages | 3 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 2012 |
| Issue number | Agosto |
| DOIs | |
| Publication status | Published - 2012 |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases
Keywords
- resistance
- tigecycline
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