In vitro effect of unacylated ghrelin and obestatin on human luteal cell function

Antonio Lanzone, Michela Sali, Giovanni Delogu, Rosanna Apa, Francesca Romani, Alessandra Familiari, Stefania Catino

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

To evaluate whether unacylated ghrelin and obestatin were able to influence human luteal cell function. The effect of these two ghrelin-related peptides on progesterone (P4), prostaglandin (PG) F(2α), PGE(2), and vascular endothelial growth factor (VEGF) release and on VEGF expression in isolated human steroidogenic cells has been investigated.
Original languageEnglish
Pages (from-to)991-996
Number of pages6
JournalFertility and Sterility
Volume97
DOIs
Publication statusPublished - 2012

Keywords

  • Acylation
  • Adult
  • Cells, Cultured
  • Cobalt
  • Dinoprost
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Ghrelin
  • Humans
  • Luteal Cells
  • Progesterone
  • RNA, Messenger
  • Real-Time Polymerase Chain Reaction
  • Vascular Endothelial Growth Factor A

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