In vitro effect of unacylated ghrelin and obestatin on human luteal cell function

Antonio Lanzone; Michela Sali; Giovanni Delogu; Rosanna Apa; Francesca Romani; Alessandra Familiari; Stefania Catino

doi:10.1016/j.fertnstert.2012.01.096

In vitro effect of unacylated ghrelin and obestatin on human luteal cell function

Antonio Lanzone, Michela Sali, Giovanni Delogu, Rosanna Apa, Francesca Romani, Alessandra Familiari, Stefania Catino

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13 Citations (Scopus)

Abstract

To evaluate whether unacylated ghrelin and obestatin were able to influence human luteal cell function. The effect of these two ghrelin-related peptides on progesterone (P4), prostaglandin (PG) F(2α), PGE(2), and vascular endothelial growth factor (VEGF) release and on VEGF expression in isolated human steroidogenic cells has been investigated.

Original language	English
Pages (from-to)	991-996
Number of pages	6
Journal	Fertility and Sterility
Volume	97
DOIs	https://doi.org/10.1016/j.fertnstert.2012.01.096
Publication status	Published - 2012

Keywords

Acylation
Adult
Cells, Cultured
Cobalt
Dinoprost
Enzyme-Linked Immunosorbent Assay
Female
Ghrelin
Humans
Luteal Cells
Progesterone
RNA, Messenger
Real-Time Polymerase Chain Reaction
Vascular Endothelial Growth Factor A

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10.1016/j.fertnstert.2012.01.096

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title = "In vitro effect of unacylated ghrelin and obestatin on human luteal cell function",

abstract = "To evaluate whether unacylated ghrelin and obestatin were able to influence human luteal cell function. The effect of these two ghrelin-related peptides on progesterone (P4), prostaglandin (PG) F(2α), PGE(2), and vascular endothelial growth factor (VEGF) release and on VEGF expression in isolated human steroidogenic cells has been investigated.",

keywords = "Acylation, Adult, Cells, Cultured, Cobalt, Dinoprost, Enzyme-Linked Immunosorbent Assay, Female, Ghrelin, Humans, Luteal Cells, Progesterone, RNA, Messenger, Real-Time Polymerase Chain Reaction, Vascular Endothelial Growth Factor A, Acylation, Adult, Cells, Cultured, Cobalt, Dinoprost, Enzyme-Linked Immunosorbent Assay, Female, Ghrelin, Humans, Luteal Cells, Progesterone, RNA, Messenger, Real-Time Polymerase Chain Reaction, Vascular Endothelial Growth Factor A",

author = "Antonio Lanzone and Michela Sali and Giovanni Delogu and Rosanna Apa and Francesca Romani and Alessandra Familiari and Stefania Catino",

year = "2012",

doi = "10.1016/j.fertnstert.2012.01.096",

language = "English",

volume = "97",

pages = "991--996",

journal = "Fertility and Sterility",

issn = "0015-0282",

publisher = "Usa: Elsevier -Highway, Birmingham, AL: American Society for Reproductive Medicine",

}

TY - JOUR

T1 - In vitro effect of unacylated ghrelin and obestatin on human luteal cell function

AU - Lanzone, Antonio

AU - Sali, Michela

AU - Delogu, Giovanni

AU - Apa, Rosanna

AU - Romani, Francesca

AU - Familiari, Alessandra

AU - Catino, Stefania

PY - 2012

Y1 - 2012

N2 - To evaluate whether unacylated ghrelin and obestatin were able to influence human luteal cell function. The effect of these two ghrelin-related peptides on progesterone (P4), prostaglandin (PG) F(2α), PGE(2), and vascular endothelial growth factor (VEGF) release and on VEGF expression in isolated human steroidogenic cells has been investigated.

AB - To evaluate whether unacylated ghrelin and obestatin were able to influence human luteal cell function. The effect of these two ghrelin-related peptides on progesterone (P4), prostaglandin (PG) F(2α), PGE(2), and vascular endothelial growth factor (VEGF) release and on VEGF expression in isolated human steroidogenic cells has been investigated.

KW - Acylation

KW - Adult

KW - Cells, Cultured

KW - Cobalt

KW - Dinoprost

KW - Enzyme-Linked Immunosorbent Assay

KW - Female

KW - Ghrelin

KW - Humans

KW - Luteal Cells

KW - Progesterone

KW - RNA, Messenger

KW - Real-Time Polymerase Chain Reaction

KW - Vascular Endothelial Growth Factor A

KW - Acylation

KW - Adult

KW - Cells, Cultured

KW - Cobalt

KW - Dinoprost

KW - Enzyme-Linked Immunosorbent Assay

KW - Female

KW - Ghrelin

KW - Humans

KW - Luteal Cells

KW - Progesterone

KW - RNA, Messenger

KW - Real-Time Polymerase Chain Reaction

KW - Vascular Endothelial Growth Factor A

UR - http://hdl.handle.net/10807/16472

U2 - 10.1016/j.fertnstert.2012.01.096

DO - 10.1016/j.fertnstert.2012.01.096

M3 - Article

VL - 97

SP - 991

EP - 996

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

ER -

In vitro effect of unacylated ghrelin and obestatin on human luteal cell function

Abstract

Keywords

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