In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species.

Brunella Posteraro, Mario Tumbarello, Giovanni Fadda, Maurizio Sanguinetti, Barbara Fiori Alfarano, Riccardo Torelli, David S Perlin

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(90)s (SMIC(90)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(90)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(90) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.
Original languageEnglish
Pages (from-to)3031-3035
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume2011
Publication statusPublished - 2011

Keywords

  • anidulafungin
  • aspergillus
  • biofilm
  • candida

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