Abstract
IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support a role for IL-18 in inflammation, allergy and immune diseases.
Original language | English |
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Pages (from-to) | 7-11 |
Number of pages | 5 |
Journal | JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS |
Publication status | Published - 2011 |
Keywords
- Interleukin 18