Il burden dell’influenza in Italia: applicazione di una nuova metodologia per il calcolo dei Disability Adjusted Life Years

Translated title of the contribution: [Autom. eng. transl.] The burden of influenza in Italy: application of a new methodology for the calculation of Disability Adjusted Life Years

Gualtiero Ricciardi, Silvia Longhi, Chiara De Waure, Francesco Di Nardo, E Franco, C Rizzo, C Gibbons, Mj Mangen, J Brooke, A Cassini, P Kramarz, M. Kretzschmar

Research output: Contribution to journalConference article

Abstract

[Autom. eng. transl.] the European Union and EEA / EFTA countries (BCoDE) ”started in 2009, Italy was chosen as a pilot country for the application of the methodology developed for calculating the burden of the main infectious diseases. The objective of this study is to present preliminary data relating to the impact of influence on the Italian population in terms of disability adjusted life years. METHODS: Starting from the approach used in the "Global Burden of Disease" study of the World Health Organization, the burden of influence for the time span 2005-2007 was calculated. Since the information system of infectious diseases does not provide for the mandatory notification of influenza (with the exception of cases confirmed in the laboratory) and the sentinel surveillance system InfluNet does not provide data broken down by gender and for the age classes considered in the study, they are hospitalization data provided by the Ministry of Health were used adjusted for a correction factor for underreporting. In the development of the outcome tree four major complications (pneumonia, otitis media, acute respiratory distress syndrome and sepsis) and their sequelae were considered, providing accurate estimates of transition probabilities, durations and disability weights. RESULTS: In the period of time under examination the burden of influence in terms of DALYs per year was equal to 24,241, while the rate per 100,000, compared to the Italian population, was equal to 39.4. The data stratified by age show, for both genders, a greater burden for the extreme age groups (0, 1-4 years and 80-84, 85+ years). The female population is most affected, especially for the age groups over 60 years. CONCLUSIONS: In consideration of the impact of influence on individuals and on society, the evaluation of disease burden is fundamental with a view to priority setting and prevention. However, in the analysis of the data it is necessary to take into account the limits deriving from the use of hospital discharge data, since the burden of the disease may be greater for those age groups that are more likely to resort to hospitalization (children and the elderly ), as confirmed by the calculation of DALYs per year. The developed methodology, which also includes correction factors for sub-reports, still makes it possible to obtain accurate estimates and is therefore also applicable to those countries where surveillance systems do not provide notification data.
Translated title of the contribution[Autom. eng. transl.] The burden of influenza in Italy: application of a new methodology for the calculation of Disability Adjusted Life Years
Original languageItalian
Pages (from-to)443-443
Number of pages1
JournalIGIENE E SANITÀ PUBBLICA
Publication statusPublished - 2011
EventXII Conferenza Nazionale di Sanità Pubblica. - Roma
Duration: 12 Oct 201115 Oct 2011

Keywords

  • Burden of disease
  • Influenza

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