IL-31 a Th2 cytokine involved in immunity and inflammation.

Ml Castellani; P. Felaco; R. J. Galzio; D. Tripodi; E. Toniato; M. A. De Lutiis; M. Fulcheri; A. Caraffa; P. Antinolfi; S. Tete; M. Felaco; F. Conti; Franco Pandolfi; T. C. Theoharides; Y. B. Shaiki Dathagirisaheb

IL-31 a Th2 cytokine involved in immunity and inflammation.

Ml Castellani, P. Felaco, R. J. Galzio, D. Tripodi, E. Toniato, M. A. De Lutiis, M. Fulcheri, A. Caraffa, P. Antinolfi, S. Tete, M. Felaco, F. Conti, Franco Pandolfi, T. C. Theoharides, Y. B. Shaiki Dathagirisaheb

Università Cattolica del Sacro Cuore

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.

Original language	English
Pages (from-to)	709-713
Number of pages	5
Journal	International Journal of Immunopathology and Pharmacology
Publication status	Published - 2010

Keywords

IL-31

Cite this

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title = "IL-31 a Th2 cytokine involved in immunity and inflammation.",

abstract = "Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.",

keywords = "IL-31, IL-31",

author = "Ml Castellani and P. Felaco and Galzio, {R. J.} and D. Tripodi and E. Toniato and {De Lutiis}, {M. A.} and M. Fulcheri and A. Caraffa and P. Antinolfi and S. Tete and M. Felaco and F. Conti and Franco Pandolfi and Theoharides, {T. C.} and {Shaiki Dathagirisaheb}, {Y. B.}",

year = "2010",

language = "English",

pages = "709--713",

journal = "International Journal of Immunopathology and Pharmacology",

issn = "0394-6320",

publisher = "SAGE Publications Inc.",

}

TY - JOUR

T1 - IL-31 a Th2 cytokine involved in immunity and inflammation.

AU - Castellani, Ml

AU - Felaco, P.

AU - Galzio, R. J.

AU - Tripodi, D.

AU - Toniato, E.

AU - De Lutiis, M. A.

AU - Fulcheri, M.

AU - Caraffa, A.

AU - Antinolfi, P.

AU - Tete, S.

AU - Felaco, M.

AU - Conti, F.

AU - Pandolfi, Franco

AU - Theoharides, T. C.

AU - Shaiki Dathagirisaheb, Y. B.

PY - 2010

Y1 - 2010

N2 - Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.

AB - Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.

KW - IL-31

UR - http://hdl.handle.net/10807/8050

M3 - Article

SN - 0394-6320

SP - 709

EP - 713

JO - International Journal of Immunopathology and Pharmacology

JF - International Journal of Immunopathology and Pharmacology

ER -

IL-31 a Th2 cytokine involved in immunity and inflammation.

Abstract

Keywords

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