Abstract

Patients with inflammatory bowel disease (IBD) have an increased risk of thrombotic complications. Moreover, a hypercoagulable state has been hypothesized as a contributing factor in the pathogenesis of IBD. Recently, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor for thromboembolic disease. We aimed to evaluate the prevalence of hyperhomocysteinemia in patients with IBD and to investigate the contribution of genetic defects in the enzymes involved in homocysteine (Hcy) metabolism and vitamin status in determining increased levels of plasma total Hcy (tHcy).
Original languageEnglish
Pages (from-to)2677-2682
Number of pages6
JournalAmerican Journal of Gastroenterology
Volume96
DOIs
Publication statusPublished - 2001

Keywords

  • Homocysteine
  • Hyperhomocysteinemia
  • Inflammatory Bowel Diseases
  • Polymorphism, Genetic
  • Prevalence

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