Human parvovirus B 19 and Epstein-Barr virus co-infection in a child with hereditary spherocytosis

Palma Maurizi, Stefano Mastrangelo, Antonio Ruggiero, Maria Giuseppina Cefalo, Ida Russo, Ilaria Sani, Riccardo Riccardi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In patients with chronic congenital haemolytic disorders, human Parvovirus B19 (HPV B19) is frequently involved in pure red-cell aplastic crises. Furthermore, it may inhibit three-lineage haematopoiesis in the bone marrow, causing severe pancytopenia. In such patients, Epstein Barr virus (EBV) infection also seems to share the same mechanism as HPV B19 in inducing bone marrow aplasia, but at present the clinical effect of an infection sustained by both viruses is unknown.
Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalEuropean Review for Medical and Pharmacological Sciences
Volume16
Publication statusPublished - 2012

Keywords

  • Anemia, Aplastic
  • Child
  • Coinfection
  • Epstein-Barr Virus Infections
  • Herpesvirus 4, Human
  • Humans
  • Male
  • Parvoviridae Infections
  • Parvovirus B19, Human
  • Spherocytosis, Hereditary

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