Human milk contains S-100B protein

Diego Gazzolo, Giovanni Monego, Valentina Corvino, Matteo Bruschettini, Pierluigi Bruschettini, Giovanni Zelano, Fabrizio Michetti

Research output: Contribution to journalArticlepeer-review

Abstract

The present study constitutes the first finding of the calcium-binding protein S100B and of its mRNA in human milk, as revealed by a quantitative immunoluminometric assay, by Western blot analysis and by reverse transcription-polymerase chain reaction (RT-PCR) assay followed by restriction enzyme digestion. The concentration of S100B in milk is markedly higher than that observed in other biological fluids such as cord blood, peripheral blood, urine, cerebrospinal fluid and amniotic fluid. This finding could be related to a possible trophic role, which has been hypothesized for the protein
Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalBIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Publication statusPublished - 2003

Keywords

  • Human Milk
  • S100B

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