HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region

Francesco Bussu; Michela Sali; Roberto Gallus; Gianluigi Petrone; Rosa Autorino; Rosaria Santangelo; Manlio Pandolfini; Francesco Miccichè; Giovanni Delogu; Giovanni Almadori; Jacopo Galli; Maurizio Sanguinetti; Guido Rindi; Massimo Tommasino; Vincenzo Valentini; Gaetano Paludetti

doi:10.1245/s10434-015-4808-5

HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region

Francesco Bussu, Michela Sali, Roberto Gallus, Gianluigi Petrone, Rosa Autorino, Rosaria Santangelo, Manlio Pandolfini, Francesco Miccichè, Giovanni Delogu, Giovanni Almadori, Jacopo Galli, Maurizio Sanguinetti, Guido Rindi, Massimo Tommasino, Vincenzo Valentini, Gaetano Paludetti

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Abstract

Approximately 1-9 % of all head and neck squamous cell carcinomas are neck metastases from clinically undetectable primary tumors. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are proven carcinogenic factors that are associated with oropharyngeal squamous cell carcinoma and nasopharyngeal carcinoma, respectively. In the present study, we evaluated the prevalence of these viruses in neck metastases from unknown primary squamous cell carcinoma.

Original language	English
Pages (from-to)	979-984
Number of pages	6
Journal	Annals of Surgical Oncology
Volume	22 Suppl 3
DOIs	https://doi.org/10.1245/s10434-015-4808-5
Publication status	Published - 2015

Keywords

HPV

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Bussu, F., Sali, M., Gallus, R., Petrone, G., Autorino, R., Santangelo, R., Pandolfini, M., Miccichè, F., Delogu, G., Almadori, G., Galli, J., Sanguinetti, M., Rindi, G., Tommasino, M., Valentini, V., & Paludetti, G. (2015). HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region. Annals of Surgical Oncology, 22 Suppl 3, 979-984. https://doi.org/10.1245/s10434-015-4808-5

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title = "HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region",

abstract = "Approximately 1-9 % of all head and neck squamous cell carcinomas are neck metastases from clinically undetectable primary tumors. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are proven carcinogenic factors that are associated with oropharyngeal squamous cell carcinoma and nasopharyngeal carcinoma, respectively. In the present study, we evaluated the prevalence of these viruses in neck metastases from unknown primary squamous cell carcinoma.",

keywords = "HPV, HPV",

author = "Francesco Bussu and Michela Sali and Roberto Gallus and Gianluigi Petrone and Rosa Autorino and Rosaria Santangelo and Manlio Pandolfini and Francesco Miccich{\`e} and Giovanni Delogu and Giovanni Almadori and Jacopo Galli and Maurizio Sanguinetti and Guido Rindi and Massimo Tommasino and Vincenzo Valentini and Gaetano Paludetti",

year = "2015",

doi = "10.1245/s10434-015-4808-5",

language = "English",

volume = "22 Suppl 3",

pages = "979--984",

journal = "Annals of Surgical Oncology",

issn = "1068-9265",

publisher = "SPRINGER, 233 SPRING STREET, NEW YORK, USA, NY, 10013",

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Bussu, F , Sali, M, Gallus, R, Petrone, G, Autorino, R, Santangelo, R, Pandolfini, M, Miccichè, F, Delogu, G, Almadori, G, Galli, J , Sanguinetti, M , Rindi, G, Tommasino, M, Valentini, V & Paludetti, G 2015, 'HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region', Annals of Surgical Oncology, vol. 22 Suppl 3, pp. 979-984. https://doi.org/10.1245/s10434-015-4808-5

TY - JOUR

T1 - HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region

AU - Bussu, Francesco

AU - Sali, Michela

AU - Gallus, Roberto

AU - Petrone, Gianluigi

AU - Autorino, Rosa

AU - Santangelo, Rosaria

AU - Pandolfini, Manlio

AU - Miccichè, Francesco

AU - Delogu, Giovanni

AU - Almadori, Giovanni

AU - Galli, Jacopo

AU - Sanguinetti, Maurizio

AU - Rindi, Guido

AU - Tommasino, Massimo

AU - Valentini, Vincenzo

AU - Paludetti, Gaetano

PY - 2015

Y1 - 2015

N2 - Approximately 1-9 % of all head and neck squamous cell carcinomas are neck metastases from clinically undetectable primary tumors. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are proven carcinogenic factors that are associated with oropharyngeal squamous cell carcinoma and nasopharyngeal carcinoma, respectively. In the present study, we evaluated the prevalence of these viruses in neck metastases from unknown primary squamous cell carcinoma.

AB - Approximately 1-9 % of all head and neck squamous cell carcinomas are neck metastases from clinically undetectable primary tumors. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are proven carcinogenic factors that are associated with oropharyngeal squamous cell carcinoma and nasopharyngeal carcinoma, respectively. In the present study, we evaluated the prevalence of these viruses in neck metastases from unknown primary squamous cell carcinoma.

KW - HPV

UR - http://hdl.handle.net/10807/72318

U2 - 10.1245/s10434-015-4808-5

DO - 10.1245/s10434-015-4808-5

M3 - Article

SN - 1068-9265

VL - 22 Suppl 3

SP - 979

EP - 984

JO - Annals of Surgical Oncology

JF - Annals of Surgical Oncology

ER -

HPV and EBV Infections in Neck Metastases from Occult Primary Squamous Cell Carcinoma: Another Virus-Related Neoplastic Disease in the Head and Neck Region

Abstract

Keywords

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