TY - JOUR
T1 - How the gut parasitome affects human health
AU - Ianiro, Gianluca
AU - Iorio, Andrea
AU - Porcari, Serena
AU - Masucci, Luca
AU - Sanguinetti, Maurizio
AU - Perno, Carlo Federico
AU - Gasbarrini, Antonio
AU - Putignani, Lorenza
AU - Cammarota, Giovanni
PY - 2022
Y1 - 2022
N2 - The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.
AB - The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.
KW - big-data omics
KW - human gut microbiome
KW - meiofauna
KW - prokaryota
KW - big-data omics
KW - human gut microbiome
KW - meiofauna
KW - prokaryota
UR - https://publicatt.unicatt.it/handle/10807/230851
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85129179026&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85129179026&origin=inward
U2 - 10.1177/17562848221091524
DO - 10.1177/17562848221091524
M3 - Article
SN - 1756-283X
VL - 15
SP - 17562848221091524-N/A
JO - Therapeutic Advances in Gastroenterology
JF - Therapeutic Advances in Gastroenterology
IS - N/A
ER -
