How the gut parasitome affects human health

Gianluca Ianiro; Andrea Iorio; Serena Porcari; Luca Masucci; Maurizio Sanguinetti; Carlo Federico Perno; Antonio Gasbarrini; Lorenza Putignani; Giovanni Cammarota

doi:10.1177/17562848221091524

How the gut parasitome affects human health

Gianluca Ianiro, Andrea Iorio, Serena Porcari, Luca Masucci, Maurizio Sanguinetti, Carlo Federico Perno, Antonio Gasbarrini, Lorenza Putignani, Giovanni Cammarota

IRCCS Ospedale pediatrico Bambino Gesù - Roma

Research output: Contribution to journal › Article

Abstract

The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.

Original language	English
Pages (from-to)	17562848221091524-N/A
Journal	Therapeutic Advances in Gastroenterology
Volume	15
DOIs	https://doi.org/10.1177/17562848221091524
Publication status	Published - 2022

Keywords

big-data omics
prokaryota
meiofauna
human gut microbiome

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/17562848221091524

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abstract = "The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.",

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T1 - How the gut parasitome affects human health

AU - Ianiro, Gianluca

AU - Iorio, Andrea

AU - Porcari, Serena

AU - Masucci, Luca

AU - Sanguinetti, Maurizio

AU - Perno, Carlo Federico

AU - Gasbarrini, Antonio

AU - Putignani, Lorenza

AU - Cammarota, Giovanni

PY - 2022

Y1 - 2022

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AB - The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.

KW - big-data omics

KW - prokaryota

KW - meiofauna

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KW - big-data omics

KW - prokaryota

KW - meiofauna

KW - human gut microbiome

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DO - 10.1177/17562848221091524

M3 - Article

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JO - Therapeutic Advances in Gastroenterology

JF - Therapeutic Advances in Gastroenterology

ER -

How the gut parasitome affects human health

Abstract

Keywords

UN SDGs

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