HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5.

Mariapaola Marino, Amelia Evoli, Emanuela Bartoccioni, Flavia Scuderi, A. Augugliaro, Sofia Chiatamonte Ranieri, Donato Sauchielli, Paolo Alboini

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

We evaluated HLA-DRB1*, DQA1*, and DQB1* allele profile in MuSK-MG in comparison with a control population and non-thymoma early onset AChR-MG (AChR-EOMG). We confirm the strong positive association of AChR-EOMG with DRB1*03 DQA1*0501 and DQB1*0201 alleles as previously reported. MuSK-MG appears to be strongly associated with DRB1*16 and DQB1*0502 alleles.
Original languageEnglish
Pages (from-to)195-197
Number of pages3
JournalNeurology
Volume2009
Publication statusPublished - 2009

Keywords

  • MHC
  • MuSK
  • myasthenia gravis

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