Hepatic encephalopathy 2018: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF)

Antonio Gasbarrini, Francesca Romana Ponziani, Sara Montagnese, Francesco Paolo Russo, Piero Amodio, Patrizia Burra, Carmela Loguercio, Giulio Marchesini, Manuela Merli, Oliviero Riggio, Carmelo Scarpignato

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Hepatic encephalopathy (HE) is a common, worrisome and sometimes difficult to manage complication of end-stage liver disease. HE is often recurrent, requiring multiple hospital admissions. It can have serious implications in terms of a patient's ability to perform complex tasks (for example driving), their earning capacity, their social and family roles. This guideline reviews current knowledge on HE definition, pathophysiology, diagnosis and treatment, both by general principles and by way of a summary of available drugs and treatment strategies. The quality of the published, pertinent evidence is graded, and practical recommendations are made. Where possible, these are placed within the Italian health service context, with reference to local diagnosis and management experience.
Original languageEnglish
Pages (from-to)190-205
JournalDIGESTIVE AND LIVER DISEASE
Volume51
DOIs
Publication statusPublished - 2019

Keywords

  • AISF
  • Gastroenterology
  • Guideline
  • Hepatic encephalopathy
  • Hepatology

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